SLA

Gene Symbol SLA
Entrez Gene 6503
Alt Symbol SLA1, SLAP
Species Human
Gene Type protein-coding
Description Src-like-adaptor
Other Description SLAP-1|hSLAP|src-like-adapter|src-like-adapter protein 1
Swissprots B7Z4L6 Q6FI01 Q13239 Q9UMQ8 B7Z4J2
Accessions CAV30731 CBX47476 CBX47477 CBX47478 EAW92159 Q13239 AJ238591 CAB53536 AK297423 BAH12578 AK297519 BAH12602 AK309401 AK310092 AK310108 AK310115 AK311010 AK312584 BAG35478 AW137142 BC007042 AAH07042 BT019994 AAV38797 BX648382 CR536537 CAG38774 D89077 BAA13758 DA483212 DA522819 DA999385 DB265860 DC313073 EU831422 ACE87109 EU831515 ACE86434 U30473 AAC50357 U44403 AAC27662 XM_011517227 XP_011515529 XM_011517228 XP_011515530 NM_001045556 NP_001039021 NM_001045557 NP_001039022 NM_001282964 NP_001269893 NM_001282965 NP_001269894 NM_006748 NP_006739
Function Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. {ECO:0000269|PubMed:10449770, ECO:0000269|PubMed:11696592}.
Subcellular Location Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Note=Colocalizes with endosomes. {ECO:0000250}.
Tissue Specificity Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9660183}.

Slap (2.11) - sc-135802 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Slap (2.11): sc-135802. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Slap (H-106) - sc-28840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Slap (H-106): sc-28840. Western blot analysis of human recombinant Slap fusion protein.

Slap (49.53) - sc-135801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Slap (49.53): sc-135801. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane localization.

Slap (C-19) - sc-1215 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SLA (EP-2) - sc-59364 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-Slap antibody - ab96620 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Slap antibody (ab96620) at 1/2000 dilutionLane 1 : 293T whole cell lysateLane 2 : A431 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-Slap antibody - ab58290 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab58290 Slap antibody at 1ug/ml.

Anti-Slap antibody - ab172126 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-Slap antibody (ab172126) at 1 µg/mlLane 1 : Slap transfected 293T cell line lysateLane 2 : Non-transfected 293T cell line lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Mouse IgG at 1/2500 dilution

Anti-Slap antibody - ab166797 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human kidney tissue labeling Slap with ab166797 at 15 µg/ml.

Anti-SLA Antibody - LS-C140509 from LifeSpan Bioscience

Prices $320.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLA Antibody (clone 2A1) - LS-C198205 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A1

Anti-SLA Antibody (aa175-225) IHC-plus™ - LS-B7959 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLA antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7959 dilution 15 ug/ml.

Anti-SLA Antibody (C-Terminus) IHC-plus™ - LS-B6827 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-SLA antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6827 concentration 5 ug/ml.

Slap Antibody - NBP2-24696 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: Slap Antibody [NBP2-24696] - Formalin-fixed, paraffin-embedded human kidney stained with SLAP antibody at 15 ug/ml. Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM sodium citrate buffer, pH 6.0 for 10-20 min followed by cooling at RT for 20 min.

Slap Antibody - NBP1-52966 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: Slap Antibody [NBP1-52966] - OVCAR-3 cell lysate, Antibody Titration: 0.2-1 ug/ml

Slap Antibody - H00006503-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: Slap Antibody [H00006503-B01] - analysis of SLA expression in transfected 293T cell line by SLA MaxPab polyclonal antibody (B01). Lane 1: SLA transfected lysate (31.20 KDa). Lane 2: Non-transfected lysate.

Slap Antibody - H00006503-B01P from Novus Biologicals

Prices $349.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: Slap Antibody [H00006503-B01P] - analysis of SLA expression in transfected 293T cell line by SLA MaxPab polyclonal antibody. Lane 1: SLA transfected lysate (30.36 KDa). Lane 2: Non-transfected lysate.

Slap Antibody - H00006503-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Slap Antibody (2A1) - H00006503-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2A1

SLAP Polyclonal Antibody - bs-13668R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLAP Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13668R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLAP Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13668R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLAP Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13668R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLAP Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13668R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SLAP Polyclonal Antibody, Cy3 Conjugated - bs-13668R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Search more