SLA

Gene Symbol SLA
Entrez Gene 6503
Alt Symbol SLA1, SLAP
Species Human
Gene Type protein-coding
Description Src-like-adaptor
Other Description SLAP-1|hSLAP|src-like-adapter|src-like-adapter protein 1
Swissprots B7Z4L6 Q6FI01 Q13239 Q9UMQ8 B7Z4J2
Accessions CAV30731 CBX47476 CBX47477 CBX47478 EAW92159 Q13239 AJ238591 CAB53536 AK297423 BAH12578 AK297519 BAH12602 AK309401 AK310092 AK310108 AK310115 AK311010 AK312584 BAG35478 AW137142 BC007042 AAH07042 BT019994 AAV38797 BX648382 CR536537 CAG38774 D89077 BAA13758 DA483212 DA522819 DA999385 DB265860 DC313073 EU831422 ACE87109 EU831515 ACE86434 U30473 AAC50357 U44403 AAC27662 XM_011517227 XP_011515529 XM_011517228 XP_011515530 NM_001045556 NP_001039021 NM_001045557 NP_001039022 NM_001282964 NP_001269893 NM_001282965 NP_001269894 NM_006748 NP_006739
Function Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. {ECO:0000269|PubMed:10449770, ECO:0000269|PubMed:11696592}.
Subcellular Location Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Note=Colocalizes with endosomes. {ECO:0000250}.
Tissue Specificity Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9660183}.

Slap CRISPR/Cas9 KO Plasmid (h) - sc-404179 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap HDR Plasmid (h) - sc-404179-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap Double Nickase Plasmid (h) - sc-404179-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap Double Nickase Plasmid (h2) - sc-404179-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap CRISPR Activation Plasmid (h) - sc-404179-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap CRISPR Activation Plasmid (h2) - sc-404179-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap Lentiviral Activation Particles (h) - sc-404179-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap Lentiviral Activation Particles (h2) - sc-404179-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

Slap siRNA (h) - sc-40971 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Slap shRNA Plasmid (h) - sc-40971-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Slap shRNA (h) Lentiviral Particles - sc-40971-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Slap RNAi - H00006503-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Slap RNAi - H00006503-R02 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

Slap RNAi - H00006503-R03 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU087581 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN19386 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND19386 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10358 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10358

SLA siRNA (Human) - CRH4398 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLA - MBS8205846 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human SLA (NM_006748.3) - SHH408108 from Creative biogene

Category siRNA
Species Reactivities Human

Human SLA siRNA - orb264900 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

SLA shRNA Plasmid (Human) - CHH4398 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

SLA miRNA 3'UTR clone - MiUTR3H-03872 from Creative biogene

Species Reactivities Human

SLA miRNA 3'UTR clone - MiUTR3H-03873 from Creative biogene

Species Reactivities Human
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