SLA

Gene Symbol	SLA
Entrez Gene	6503
Alt Symbol	SLA1, SLAP
Species	Human
Gene Type	protein-coding
Description	Src-like-adaptor
Other Description	SLAP-1|hSLAP|src-like-adapter|src-like-adapter protein 1
Swissprots	B7Z4L6 Q6FI01 Q13239 Q9UMQ8 B7Z4J2
Accessions	CAV30731 CBX47476 CBX47477 CBX47478 EAW92159 Q13239 AJ238591 CAB53536 AK297423 BAH12578 AK297519 BAH12602 AK309401 AK310092 AK310108 AK310115 AK311010 AK312584 BAG35478 AW137142 BC007042 AAH07042 BT019994 AAV38797 BX648382 CR536537 CAG38774 D89077 BAA13758 DA483212 DA522819 DA999385 DB265860 DC313073 EU831422 ACE87109 EU831515 ACE86434 U30473 AAC50357 U44403 AAC27662 XM_011517227 XP_011515529 XM_011517228 XP_011515530 NM_001045556 NP_001039021 NM_001045557 NP_001039022 NM_001282964 NP_001269893 NM_001282965 NP_001269894 NM_006748 NP_006739
Function	Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins. {ECO:0000269|PubMed:10449770, ECO:0000269|PubMed:11696592}.
Subcellular Location	Cytoplasm {ECO:0000250}. Endosome {ECO:0000250}. Note=Colocalizes with endosomes. {ECO:0000250}.
Tissue Specificity	Expressed in lung and fetal brain. Weakly expressed in heart, adult brain, placenta, liver, skeletal muscle, kidney and pancreas. {ECO:0000269|PubMed:9660183}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-SLA-cDNA-Clone - DC02065 from Abgent, a WuXi AppTec company Prices $372.60 Sizes 10 µg Species Human Accession BC007042

SLA - MBS1273974 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC007042

Human SLA cDNA clone(NM_001045557.2) - CDFH017630 from Creative Biomart Species Human Accession NM_001045557.2

Human SLA cDNA clone(NM_006748.3) - CDFH017631 from Creative Biomart Species Human Accession NM_006748.3

Human SLA ORF Clone(NM_006748.3) - CDCL175559 from Creative Biomart Species Human Accession NM_006748.3

Human SLA ORF Clone(NM_006748.3) - CDCR293611 from Creative Biomart Species Human Accession NM_006748.3

Human SLA ORF Clone(NM_006748.3) - CDCR293613 from Creative Biomart Species Human Accession NM_006748.3

Human SLA ORF Clone(NM_001045556.2) - CDCR344820 from Creative Biomart Species Human Accession NM_001045556.2

Human SLA ORF Clone(NM_001045556.2) - CDCR344821 from Creative Biomart Species Human Accession NM_001045556.2

Human SLA ORF Clone(NM_001045557.2) - CDCR344822 from Creative Biomart Species Human Accession NM_001045557.2

Human SLA ORF Clone(NM_001045557.2) - CDCR344823 from Creative Biomart Species Human Accession NM_001045557.2

Human SLA ORF Clone(NM_001045557.2) - CDCR344824 from Creative Biomart Species Human Accession NM_001045557.2

Human SLA ORF Clone(NM_001045557.2) - CDCR344825 from Creative Biomart Species Human Accession NM_001045557.2

Human SLA ORF Clone(NM_006748.3) - CDCR293611 from Creative biogene Species Human

Human SLA ORF Clone(NM_001045556.2) - CDCR344820 from Creative biogene Species Human

Human SLA ORF Clone(NM_001045557.2) - CDCR344822 from Creative biogene Species Human

Human SLA ORF Clone (BC007042) - CDCS407152 from Creative biogene Species Human Accession Q13239

Human SLA cDNA Clone(NM_001045557.2) - CDFH017630 from Creative biogene Species Human

Human SLA cDNA Clone(NM_006748.3) - CDFH017631 from Creative biogene Species Human

Human SLA Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG12748-ANR from Sino Biological Species Human

Human SLA Gene ORF cDNA clone expression plasmid, C-Flag tag - HG12748-CF from Sino Biological Species Human

Human SLA Gene ORF cDNA clone expression plasmid, C-His tag - HG12748-CH from Sino Biological Species Human

Human SLA Gene ORF cDNA clone expression plasmid, C-HA tag - HG12748-CY from Sino Biological Species Human

Human SLA Gene ORF cDNA clone expression plasmid, N-Myc tag - HG12748-NM from Sino Biological Species Human

Human SLA Gene ORF cDNA clone in cloning vector - HG12748-U from Sino Biological Species Human

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