SMARCC2

Gene Symbol SMARCC2
Entrez Gene 6601
Alt Symbol BAF170, CRACC2, Rsc8
Species Human
Gene Type protein-coding
Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Other Description BRG1-associated factor 170|SWI/SNF complex 170 kDa subunit|SWI/SNF complex subunit SMARCC2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2|SWI3-like protein|chromatin remodeling complex BAF170 subunit|mammalian chromatin remodeling complex BRG1-associated factor 170
Swissprots Q96GY4 Q96E12 Q8TAQ2 Q59GV3 F8VTJ5 Q92923
Accessions EAW96906 EAW96907 EAW96908 Q8TAQ2 AB209006 BAD92243 AB209293 BAD92530 AK025128 AK293896 BAG57283 AK315153 AL833124 CAH56218 BC009067 AAH09067 BC013045 AAH13045 BC026222 AAH26222 BC040645 BE326466 BQ272432 BT009924 AAP88926 BX476347 CB850719 CX165574 EU176256 ABW03707 U66616 AAC50694 XM_005269101 XP_005269158 XM_005269102 XP_005269159 XM_005269103 XP_005269160 XM_005269104 XP_005269161 XM_011538693 XP_011536995 XM_011538694 XP_011536996 NM_001130420 NP_001123892 NM_003075 NP_003066 NM_139067 NP_620706
Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACT
Subcellular Location Nucleus.
Tissue Specificity Ubiquitously expressed.

SMARCC2/BAF170 Antibody - 8829 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using SMARCC2/BAF170 Antibody.

SMARCC2/BAF170 (D8O9V) Rabbit mAb - 12760 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D8O9V
Western blot analysis of extracts from various cell lines using SMARCC2/BAF170 (D8O9V) Rabbit mAb.

BAF170 (C-19) - sc-9744 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BAF170 (C-19): sc-9744. Western blot analysis of BAF170 expression in non-transfected: sc-110760 (A) and human BAF170 transfected: sc-111021 (B) 293 whole cell lysates.

BAF170 (G-12) - sc-166237 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF170 (G-12): sc-166237. Immunofluorescence staining of formalin-fixed HeLa cells showing nuclear localization. Kindly provided by Yang Xiang, Ph.D., Division of Newborn Medicine, Boston Childrens Hospital, Cell Biology Department, Harvard Medical School.

BAF170 (E-6) - sc-17838 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BAF170 (E-6): sc-17838. Immunoperoxidase staining of formalin fixed, paraffin-embedded human epididymis tissue showing nuclear staining of glandular cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

BAF170 (H-116) - sc-10757 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
BAF170 (H-116): sc-10757. Western blot analysis of BAF170 expression in A-431 nuclear extract.

BAF170 (N-19) - sc-9742 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
BAF170 (N-19): sc-9742. Western blot analysis of BAF170 expression in non-transfected: sc-110760 (A) and human BAF170 transfected: sc-111021 (B) 293 whole cell lysates.

Anti-SMRC2 antibody - ab71907 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SMRC2 antibody (ab71907) at 1 µg/mlLane 1 : Raji (Human Burkitt's lymphoma cell line) Whole Cell Lysate Lane 2 : SK N SH (Human neuroblastoma) Whole Cell Lysate Lysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutionPerformed under reducing conditions.

Anti-SMRC2 antibody - ab135121 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SMRC2 antibody (ab135121) at 1/1000 dilution + Total cell extracts from Human HeLa

Anti-SMRC2 antibody - ab64853 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SMRC2 antibody (ab64853) at 1/500 dilutionLane 1 : Extracts from HUVEC cellsLane 2 : Extracts from COLO205 cellsLane 3 : Extracts from COLO205 cells with immunising peptide at 10 µgLysates/proteins at 30 µg per lane.

Anti-SMARCC2 Antibody (aa575-625) - LS-C287878 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SMARCC2 Antibody - LS-C332027 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SMARCC2 Antibody (Met388) - LS-C176824 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of BAF170 (M388) pAb in extracts from HUVEC cells.

Anti-SMARCC2 Antibody (aa254-303) - LS-C206181 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SMARCC2 antibody Western Blot of HepG2. Antibody dilution: 1 ug/ml.

Anti-SMARCC2 Antibody (C-Terminus) - LS-C287869 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human SMARCC2/BAF170 by Immunohistochemistry. Sample: FFPE section of human skin basal cell carcinoma. Antibody: Affinity purified rabbit anti-SMARCC2/BAF170 used at a dilution of 1:200 (1 ug/ml). Detection: DAB.

Anti-SMARCC2 Antibody - LS-C331791 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of HeLa cell line, using SMARCC2 antibody.

Anti-SMARCC2 Antibody (aa361-410) - LS-C119160 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of extracts from HUVEC/COLO205 cells, using SMRC2 Antibody. The lane on the right is treated with the synthesized peptide.

Anti-SMARCC2 Antibody (C-Terminus) - LS-C286461 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse SMARCC2/BAF170 by Immunohistochemistry. Sample: FFPE section of mouse squamous cell carcinoma. Antibody: Affinity purified rabbit anti-SMARCC2/BAF170 used at a dilution of 1:500.

SMARCC2/BAF170 Antibody - NBP1-90017 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SMARCC2/BAF170 Antibody [NBP1-90017] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

SMARCC2/BAF170 Antibody - NB100-92393 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: SMARCC2/BAF170 Antibody [NB100-92393] - Western blot (WB) analysis of SMARCC2/BAF170 (M388) antibody in extracts from HUVEC cells.

Anti-SMARCC2 antibody produced in rabbit - HPA021213 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SMARCC2: <B>Cat. No. HPA021213</B>: Immunohistochemical staining of human stomach shows strong nuclear positivity in glandular cells.

Anti-SMARCC2 (401-415) antibody produced in rabbit - SAB1100599 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SMARCC2 (401-415) : <B>Cat. No. SAB1100599</B>: Immunofluorescence of HUVEC cells using SMARCC2 (401-415) , Cat. No. SAB1100599 (red) at a 1:50 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SMARCC2 (101-115) antibody produced in rabbit - SAB1100598 from Sigma-Aldrich

Prices $328.50
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-SMARCC2 (101-115) : <B>Cat. No. SAB1100598</B>: Immunofluorescence of HUVEC cells using SMARCC2 (101-115) , Cat. No. SAB1100598 (red) at a 1:100 dilution, taken at 40x magnification and nuclear staining with Hoescht 33342 (blue).Yale HTCB IF procedure used. Images have been adjusted to improve viewing quality. If you would like the original image, please send a request to protocols@sial.com

Anti-SMRC2 antibody produced in rabbit - SAB4502821 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SMRC2, N-Terminal: <B>Cat. No. SAB4502821</B>: Immunoblotting analysis of extracts from HuvEc/COLO205 cells, using Anti-SMRC2, N-Terminal antibody. The lane on the left was treated with the Anti-SMRC2, N-Terminal antibody. The lane on the right (negative control) was treated with both Anti-SMRC2, N-Terminal antibody and the synthesized immunogen peptide.

SMARCC2 Antibody - N-terminal region (ARP72901_P050) - ARP72901_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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