SMARCC2

Gene Symbol	SMARCC2
Entrez Gene	6601
Alt Symbol	BAF170, CRACC2, Rsc8
Species	Human
Gene Type	protein-coding
Description	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Other Description	BRG1-associated factor 170|SWI/SNF complex 170 kDa subunit|SWI/SNF complex subunit SMARCC2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2|SWI3-like protein|chromatin remodeling complex BAF170 subunit|mammalian chromatin remodeling complex BRG1-associated factor 170
Swissprots	Q96GY4 Q96E12 Q8TAQ2 Q59GV3 F8VTJ5 Q92923
Accessions	EAW96906 EAW96907 EAW96908 Q8TAQ2 AB209006 BAD92243 AB209293 BAD92530 AK025128 AK293896 BAG57283 AK315153 AL833124 CAH56218 BC009067 AAH09067 BC013045 AAH13045 BC026222 AAH26222 BC040645 BE326466 BQ272432 BT009924 AAP88926 BX476347 CB850719 CX165574 EU176256 ABW03707 U66616 AAC50694 XM_005269101 XP_005269158 XM_005269102 XP_005269159 XM_005269103 XP_005269160 XM_005269104 XP_005269161 XM_011538693 XP_011536995 XM_011538694 XP_011536996 NM_001130420 NP_001123892 NM_003075 NP_003066 NM_139067 NP_620706
Function	Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACT
Subcellular Location	Nucleus.
Tissue Specificity	Ubiquitously expressed.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SMRC2 full length protein - ab116997 from Abcam Category Protein Source Wheat germ Species Human

Human SMRC2 peptide - ab71906 from Abcam Category Peptide

Recombinant Human SMARCC2/BAF170 Protein - H00006601-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

SMARCC2 / BAF170 - H00006601-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

SMARCC2 / BAF170 - H00006601-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

BAF170 fusion protein - Ag2634 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

BAF170 fusion protein - ag19234 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human SMARCC2 - SMARCC2-31424TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human SMARCC2, MYC/DDK-tagged - SMARCC2-2416H from Creative Biomart Category Protein Source HEK293 Species Human

BAF170 Blocking Peptide - CBP3319 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

BAF170 (M388) Peptide - BS2101P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human SWI/SNF complex subunit SMARCC2(SMARCC2) ,partial - CSB-YP851527HU CSB-EP851527HU CSB-BP851527HU CSB-MP851527HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SMARCC2 / BAF170 (transcript variant 2) - TP303774 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

SMARCC2/BAF170 Recombinant Protein Antigen - NBP1-90017PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

BAF170 Blocking Peptide - abx162181 from Abbexa Category Peptide Species Human, Mouse, Rat

SMARCC2 Peptide, Human - M34GP14730H from Creative Peptides Category Peptide Source Synthetic. Species Human

BAF170 Peptide - orb224205 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

SWI/SNF complex subunit SMARCC2 (SMARCC2), partial, Recombinant Protein - MBS1384102 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SMARCC2/BAF170 Recombinant Protein Antigen - NBP2-57277PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

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