SMARCC2

Gene Symbol SMARCC2
Entrez Gene 6601
Alt Symbol BAF170, CRACC2, Rsc8
Species Human
Gene Type protein-coding
Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
Other Description BRG1-associated factor 170|SWI/SNF complex 170 kDa subunit|SWI/SNF complex subunit SMARCC2|SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2|SWI3-like protein|chromatin remodeling complex BAF170 subunit|mammalian chromatin remodeling complex BRG1-associated factor 170
Swissprots Q96GY4 Q96E12 Q8TAQ2 Q59GV3 F8VTJ5 Q92923
Accessions EAW96906 EAW96907 EAW96908 Q8TAQ2 AB209006 BAD92243 AB209293 BAD92530 AK025128 AK293896 BAG57283 AK315153 AL833124 CAH56218 BC009067 AAH09067 BC013045 AAH13045 BC026222 AAH26222 BC040645 BE326466 BQ272432 BT009924 AAP88926 BX476347 CB850719 CX165574 EU176256 ABW03707 U66616 AAC50694 XM_005269101 XP_005269158 XM_005269102 XP_005269159 XM_005269103 XP_005269160 XM_005269104 XP_005269161 XM_011538693 XP_011536995 XM_011538694 XP_011536996 NM_001130420 NP_001123892 NM_003075 NP_003066 NM_139067 NP_620706
Function Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACT
Subcellular Location Nucleus.
Tissue Specificity Ubiquitously expressed.

SMARCC2 - MBS1276638 from MyBioSource

Prices $175.00
Sizes 10ug plasmid + 200ul glycerol stock
Species Human
Accession BC013045

Human SMARCC2 cDNA clone(NM_001130420.1) - CDFH018154 from Creative Biomart

Species Human
Accession NM_001130420.1

Human SMARCC2 ORF Clone(NM_001130420.1) - CDCR349522 from Creative Biomart

Species Human
Accession NM_001130420.1

Human SMARCC2 ORF Clone(NM_001130420.1) - CDCR349526 from Creative Biomart

Species Human
Accession NM_001130420.1

Human SMARCC2 ORF Clone(NM_001130420.1) - CDCL176359 from Creative Biomart

Species Human
Accession NM_001130420.1

Human SMARCC2 ORF Clone(NM_003075.3) - CDCL176360 from Creative Biomart

Species Human
Accession NM_003075.3

human SMARCC2 ORF clone - CDCH083460 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083461 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083462 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083463 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083464 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083465 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083466 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone - CDCH083467 from Creative Biomart

Species Human
Accession NM_001130420

human SMARCC2 ORF clone (NM_001130420.1) - CDCH083462 from Creative biogene

Species Human

human SMARCC2 ORF clone (NM_139067.2) - CDCH083464 from Creative biogene

Species Human

Human SMARCC2 ORF Clone (BC013045) - CDCS407933 from Creative biogene

Species Human
Accession Q8TAQ2

Human SMARCC2 cDNA Clone(NM_001130420.1) - CDFH018154 from Creative biogene

Species Human
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