MYLK2

Gene Symbol MYLK2
Entrez Gene 85366
Alt Symbol KMLC, MLCK, MLCK2, skMLCK
Species Human
Gene Type protein-coding
Description myosin light chain kinase 2
Other Description myosin light chain kinase 2, skeletal muscle|myosin light chain kinase 2, skeletal/cardiac muscle
Swissprots Q96I84 Q569L1 Q9H1R3
Accessions EAW76414 EAW76415 EAW76416 EAW76417 Q9H1R3 AF325549 AAK15494 AJ272502 CAC81354 BC007753 AAH07753 BC069627 AAH69627 BC092413 AAH92413 BC127622 AAI27623 BX647635 F22840 XR_244155 NM_033118 NP_149109
Function Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain. {ECO:0000269|PubMed:11733062}.
Subcellular Location Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Tissue Specificity Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.
Top Pathways Focal adhesion, Calcium signaling pathway, Vascular smooth muscle contraction, Gastric acid secretion, Oxytocin signaling pathway

MYLK2 (H-224) - sc-50516 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

MYLK2 (R-19) - sc-9456 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MYLK2 (R-19): sc-9456. Western blot analysis of MYLK2 expression in L8 whole cell lysate.

MYLK2 (MY-21) - sc-58803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl ascites
Host Mouse
Clonality Monoclonal

Anti-MYLK2 antibody - ab57944 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57944 MYLK2 antibody at 1ug/ml.

Anti-MYLK2 antibody - N-terminal - ab71827 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MYLK2 antibody - N-terminal (ab71827) at 1/100 dilution + Jurkat cell lysate at 12.5 µgSecondaryHRP-anti-rabbit

MYLK2 Antibody - NBP2-32489 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MYLK2 Antibody [NBP2-32489] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp

MYLK2 Antibody - NBP2-32497 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: MYLK2 Antibody [NBP2-32497] - Staining of human skeletal muscle shows moderate cytoplasmic positivity in myocytes.

MYLK2 Antibody (2G1) - H00085366-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G1
Western Blot: MYLK2 Antibody (2G1) [H00085366-M01] - Analysis of MYLK2 over-expressed 293 cell line, cotransfected with MYLK2 Validated Chimera RNAi ( Cat # H00085366-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with MYLK2 monoclonal antibody (M01), clone 2G1 (Cat # H00085366-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

MYLK2 Antibody - NBP2-11574 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: MYLK2 Antibody [NBP2-11574] - (0.03ug/ml) staining of Human Colon lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

MYLK2 Antibody - H00085366-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: MYLK2 Antibody [H00085366-B01] - analysis of MYLK2 expression in transfected 293T cell line by MYLK2 MaxPab polyclonal antibody. Lane 1: MYLK2 transfected lysate (65.56 KDa). Lane 2: Non-transfected lysate.

MYLK2 Antibody - H00085366-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MYLK2 Antibody - H00085366-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

MYLK2 Polyclonal Antibody - bs-9866R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MYLK2 antibody produced in rabbit - HPA059890 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MYLK2: <B>Cat. No. HPA059890</B>: Immunohistochemical staining of Human skeletal muscle shows moderate cytoplasmic positivity in myocytes.

Anti-MYLK2 (181-195) antibody produced in rabbit - SAB1105884 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human MYLK2 was separated on SDS-PAGE, blotted with Anti-MYLK2 (181-195) (<B>Cat. No. SAB1105884</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:1,000<BR/>2. Antibody dilution 1:1,000 + MYLK2 immunizing peptide (human, 181-195)<BR/>3. ”Anti-FLAG” antibody (<B>Cat. No. F7425</B>), working concentration 2 μg/mL

Anti-MYLK2 antibody produced in rabbit - HPA059704 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MYLK2: <B>Cat. No. HPA059704</B>: Immunohistochemical staining of Human skeletal muscle shows moderate cytoplasmic positivity in myocytes.

Anti-MYLK2 antibody produced in mouse - SAB1409913 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-MYLK2: <B>Cat. No. SAB1409913</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~65.6 kDa using MYLK2 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Monoclonal Anti-MYLK2 antibody produced in mouse - WH0085366M1 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2G1
<B>Immunoblotting</B><BR/>Monoclonal Anti-MYLK2, <B>Cat. No. WH0085366M1</B> used at the antibody concentration: 1 μg/mL. Specific band of ~37 kDa using immunogen protein lysate.

MYLK2 antibody [N3C3-2] - GTX111514 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-MYLK2 antibody [N3C3-2] used in IHC (Formalin-fixed paraffin-embedded sections). GTX111514

MYLK2 antibody - 70R-18716 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

MYLK2 Antibody - abx037057 from Abbexa

Host Rabbit
Clonality Polyclonal

MLCK2 antibody - H00085366-A01 from Acris Antibodies

Prices $300.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MLCK2 antibody - H00085366-B01 from Acris Antibodies

Prices $360.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot analysis of MYLK2 expression in transfected 293T cell line (H00085366-T01) by MYLK2 MaxPab polyclonal antibody.Lane 1: MYLK2 tra

MLCK2 antibody - H00085366-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

MLCK2 antibody - H00085366-D01P from Acris Antibodies

Prices $390.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot analysis of MYLK2 expression in transfected 293T cell line (H00085366-T02) by MYLK2 MaxPab polyclonal antibody. Lane 1: MYLK2 transfected lysate(64.70 KDa). Lane 2: Non-transfected lysate.
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