MYLK2

Gene Symbol	MYLK2
Entrez Gene	85366
Alt Symbol	KMLC, MLCK, MLCK2, skMLCK
Species	Human
Gene Type	protein-coding
Description	myosin light chain kinase 2
Other Description	myosin light chain kinase 2, skeletal muscle|myosin light chain kinase 2, skeletal/cardiac muscle
Swissprots	Q96I84 Q569L1 Q9H1R3
Accessions	EAW76414 EAW76415 EAW76416 EAW76417 Q9H1R3 AF325549 AAK15494 AJ272502 CAC81354 BC007753 AAH07753 BC069627 AAH69627 BC092413 AAH92413 BC127622 AAI27623 BX647635 F22840 XR_244155 NM_033118 NP_149109
Function	Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain. {ECO:0000269|PubMed:11733062}.
Subcellular Location	Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Tissue Specificity	Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.
Top Pathways	Focal adhesion, Calcium signaling pathway, Vascular smooth muscle contraction, Gastric acid secretion, Oxytocin signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MYLK2 CRISPR/Cas9 KO Plasmid (h) - sc-406143 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 HDR Plasmid (h) - sc-406143-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 Double Nickase Plasmid (h) - sc-406143-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 Double Nickase Plasmid (h2) - sc-406143-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 CRISPR Activation Plasmid (h) - sc-406143-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 CRISPR Activation Plasmid (h2) - sc-406143-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 Lentiviral Activation Particles (h) - sc-406143-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 Lentiviral Activation Particles (h2) - sc-406143-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

MYLK2 siRNA (h) - sc-72063 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MYLK2 shRNA Plasmid (h) - sc-72063-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MYLK2 shRNA (h) Lentiviral Particles - sc-72063-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MYLK2 RNAi - H00085366-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MYLK2 RNAi - H00085366-R02 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU005361 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

MISSION® siRNA - SIHK1354 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1355 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1356 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN14840 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14840 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MYLK2 siRNA (Human) - CRJ3789 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human MYLK2 (NM_033118.3) - SHH348012 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human MYLK2(NM_033118.3) - SHH212321 from Creative biogene Category siRNA Species Reactivities Human

MYLK2 shRNA Plasmid (Human) - CHJ3789 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

MYLK2 miRNA 3'UTR clone - MiUTR1H-06588 from Creative biogene Species Reactivities Human

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