Gene Symbol | MYLK2 |
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Entrez Gene | 85366 |
Alt Symbol | KMLC, MLCK, MLCK2, skMLCK |
Species | Human |
Gene Type | protein-coding |
Description | myosin light chain kinase 2 |
Other Description | myosin light chain kinase 2, skeletal muscle|myosin light chain kinase 2, skeletal/cardiac muscle |
Swissprots | Q96I84 Q569L1 Q9H1R3 |
Accessions | EAW76414 EAW76415 EAW76416 EAW76417 Q9H1R3 AF325549 AAK15494 AJ272502 CAC81354 BC007753 AAH07753 BC069627 AAH69627 BC092413 AAH92413 BC127622 AAI27623 BX647635 F22840 XR_244155 NM_033118 NP_149109 |
Function | Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain. {ECO:0000269|PubMed:11733062}. |
Subcellular Location | Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils. |
Tissue Specificity | Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue. |
Top Pathways | Focal adhesion, Calcium signaling pathway, Vascular smooth muscle contraction, Gastric acid secretion, Oxytocin signaling pathway |
Active human MYLK2 full length protein - ab84800 from Abcam
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Human MYLK2 full length protein - ab164747 from Abcam
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Human MYLK2 protein fragment - ab164748 from Abcam
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MYLK2 Recombinant Protein - H00085366-P01 from Novus Biologicals
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MYLK2 Partial Recombinant Protein - H00085366-Q01 from Novus Biologicals
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Recombinant Human MYLK2 Protein - P4730 from Novus Biologicals
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MLCK2 - H00085366-P01-10 from Acris Antibodies
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MLCK2 - H00085366-P01-25 from Acris Antibodies
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MLCK2 - H00085366-Q01-10 from Acris Antibodies
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MLCK2 - H00085366-Q01-25 from Acris Antibodies
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MLCK2 - P4730 from Acris Antibodies
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MLCK2 - P5801 from Acris Antibodies
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MYLK2 fusion protein - ag15424 from Proteintech Group
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Recombinant Human Myosin Light Chain Kinase 2, His-tagged, Active - MYLK2-365H from Creative Biomart
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Recombinant Human MYLK2, His-tagged - MYLK2-30269TH from Creative Biomart
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Recombinant Human Myosin Light Chain Kinase 2, GST-tagged - MYLK2-1273H from Creative Biomart
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Recombinant Human MYLK2 (Active), His-tagged - MYLK2-1435H from Creative Biomart
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Recombinant Myosin Light Chain Kinase 2 (MYLK2) - RPD428Hu01 from Uscn Life Science Inc.
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Recombinant Myosin Light Chain Kinase 2 (MYLK2) - RPD428Mu01 from Uscn Life Science Inc.
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Recombinant Myosin Light Chain Kinase 2 (MYLK2) - RPD428Ra01 from Uscn Life Science Inc.
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Recombinant Myosin Light Chain Kinase 2 (MYLK2) - RPD428Hu01 from Cloud-clone
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Recombinant Human Myosin light chain kinase 2, skeletal/cardiac muscle(MYLK2) - CSB-YP863953HU CSB-EP863953HU CSB-BP863953HU CSB-MP863953HU from Cusabio
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Myosin Light Chain Kinase 2 Protein (Recombinant) - abx166940 from Abbexa
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MLCK2 - TP313583 from Acris Antibodies
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Recombinant Human MYLK2 Active GST-His - CRM026 from Cell Science
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