FNBP1L

Gene Symbol	FNBP1L
Entrez Gene	54874
Alt Symbol	C1orf39, TOCA1
Species	Human
Gene Type	protein-coding
Description	formin binding protein 1-like
Other Description	formin-binding protein 1-like|toca-1|transducer of Cdc42-dependent actin assembly 1|transducer of Cdc42-dependent actin assembly protein 1
Swissprots	Q9NXG1 Q6R4Q4 Q6B097 Q6P653 J3QSS4 Q5T0N5 Q5T0N6
Accessions	CAC22513 EAW73069 EAW73070 EAW73071 Q5T0N5 AK000282 BAA91051 AK025526 AK026988 AK296767 BAG59347 AK299760 BAG61649 AK299943 BAG61773 AK315981 BAH14352 AY514449 AAR98814 BC062477 AAH62477 BC074891 AAH74891 BC074892 AAH74892 BX476921 DB219295 DW423801 XM_011541625 XP_011539927 XM_011541626 XP_011539928 NM_001024948 NP_001020119 NM_001164473 NP_001157945 NM_017737 NP_060207
Function	Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens. {ECO:0000269|PubMed:15260990, ECO:0000269|PubMed:16326391, ECO:0000269|PubMed:19342671}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16757518}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Formin-binding protein 1-like, FNBP1L, ELISA Kit - MBS9304856 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Formin-binding protein 1-like, FNBP1L, ELISA Kit - MBS9304673 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Formin-binding protein 1-like, FNBP1L, ELISA Kit - MBS9305587 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human FNBP1L ELISA Kit - E015445 from Biobool Category ELISA Kit

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