FNBP1L

Gene Symbol	FNBP1L
Entrez Gene	54874
Alt Symbol	C1orf39, TOCA1
Species	Human
Gene Type	protein-coding
Description	formin binding protein 1-like
Other Description	formin-binding protein 1-like|toca-1|transducer of Cdc42-dependent actin assembly 1|transducer of Cdc42-dependent actin assembly protein 1
Swissprots	Q9NXG1 Q6R4Q4 Q6B097 Q6P653 J3QSS4 Q5T0N5 Q5T0N6
Accessions	CAC22513 EAW73069 EAW73070 EAW73071 Q5T0N5 AK000282 BAA91051 AK025526 AK026988 AK296767 BAG59347 AK299760 BAG61649 AK299943 BAG61773 AK315981 BAH14352 AY514449 AAR98814 BC062477 AAH62477 BC074891 AAH74891 BC074892 AAH74892 BX476921 DB219295 DW423801 XM_011541625 XP_011539927 XM_011541626 XP_011539928 NM_001024948 NP_001020119 NM_001164473 NP_001157945 NM_017737 NP_060207
Function	Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL/N-WASP-WASPIP/WIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens. {ECO:0000269|PubMed:15260990, ECO:0000269|PubMed:16326391, ECO:0000269|PubMed:19342671}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:16757518}. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, cell cortex {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human FNBP1L protein fragment - ab162869 from Abcam Category Protein Source Wheat germ Species Human

TOCA1 / FNBP1L Antibody Blocking Peptide - LS-E4297 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TOCA1 / FNBP1L Antibody Blocking Peptide - LS-E30408 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TOCA1 / FNBP1L Antibody Blocking Peptide - LS-E30409 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human FNBP1L Protein - H00054874-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

FNBP1L Blocking Peptide - NBP1-76845PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

FNBP1L Blocking Peptide - NBP1-76846PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

FNBP1L-Antibody-Center-Blocking-Peptide - BP16582c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

TOCA-1 Peptide - GTX85424-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

TOCA-1 Peptide - GTX85425-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

FNBP1L - H00054874-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

FNBP1L - H00054874-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

FNBP1L Control Peptide - AP30925CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

FNBP1L Control Peptide - AP30926CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

TOCA-1 Peptide - 4375P from ProSci Category Peptide Species Human

TOCA-1 Peptide - 4373P from ProSci Category Peptide Species Human

Recombinant Human Formin-binding protein 1-like(FNBP1L) - CSB-YP722560HU CSB-EP722560HU CSB-BP722560HU CSB-MP722560HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

FNBP1L Recombinant Protein Antigen - NBP2-49439PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

FNBP1L Peptide, Human - M34GP05809H from Creative Peptides Category Peptide Source Synthetic. Species Human

Formin-binding protein 1-like (FNBP1L), Recombinant Protein - MBS1412764 from MyBioSource Category Protein Prices $1,400.00, $1,400.00, $1,625.00, $1,625.00, $2,355.00, $2,355.00, $2,800.00, $2,800.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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