Gene Symbol | EEF2K |
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Entrez Gene | 29904 |
Alt Symbol | HSU93850, eEF-2K |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic elongation factor 2 kinase |
Other Description | calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase|calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase|calmodulin-dependent protein kinase III|eEF-2 kinase|elongation factor-2 kinase|eukaroytic elongation factor 2 kinase|eukaryotic elongation factor-2 kinase |
Swissprots | O00418 Q8N588 |
Accessions | EAW50604 O00418 AK022569 AK308757 AW675420 BC032665 AAH32665 CA397138 DA556486 DA735877 DQ890896 ABM81822 DQ894050 ABM84976 U93850 AAB58270 XR_950786 XR_950787 NM_013302 NP_037434 |
Function | Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. {ECO:0000269|PubMed:14709557, ECO:0000269|PubMed:9144159}. |
Top Pathways | Oxytocin signaling pathway, AMPK signaling pathway |
Human/Rat Phospho-EEF2K (Ser366) ELISA Kit (Cell-Based Phosphorylation ELISA) - LS-F1086 from LifeSpan Bioscience
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Human/Rat EEF2K ELISA Kit (Cell-Based ELISA) - LS-F1954 from LifeSpan Bioscience
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Mouse EEF2K ELISA Kit (Sandwich ELISA) - LS-F11353 from LifeSpan Bioscience
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Eukaryotic elongation factor 2 kinase, EEF2K, Human, ELISA Kit - E11481h from ARP American Research Products
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eEF2K Colorimetric Cell-Based ELISA Kit - CB5221 from Assay Biotechnology
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eEF2K (Phospho-Ser366) Colorimetric Cell-Based ELISA Kit - CBP1064 from Assay Biotechnology
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Rat EEF2K ELISA Kit (Custom ELISA) - LS-F16201 from LifeSpan Bioscience
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Human EEF2K ELISA Kit (Custom ELISA) - LS-F16202 from LifeSpan Bioscience
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eEF2K ELISA Kit - DEIA-XYA573 from Creative Diagnostics
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eEF2K (Phospho-Ser366) ELISA Kit - DEIA-XYA574 from Creative Diagnostics
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Human EEF2K ELISA Kit - E013709 from Biobool
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Eukaryotic elongation factor 2 kinase, ELISA Kit - MBS2884402 from MyBioSource
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Eukaryotic elongation factor 2 kinase, ELISA Kit - MBS762284 from MyBioSource
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Mouse EEF2K ELISA Kit (Sandwich ELISA) - LS-F33695 from LifeSpan Bioscience
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eEF2K Colorimetric Cell-Based ELISA Kit - EKA50189 from Biomatik
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