Gene Symbol | EEF2K |
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Entrez Gene | 29904 |
Alt Symbol | HSU93850, eEF-2K |
Species | Human |
Gene Type | protein-coding |
Description | eukaryotic elongation factor 2 kinase |
Other Description | calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase|calcium/calmodulin-dependent eukaryotic elongation factor-2 kinase|calmodulin-dependent protein kinase III|eEF-2 kinase|elongation factor-2 kinase|eukaroytic elongation factor 2 kinase|eukaryotic elongation factor-2 kinase |
Swissprots | O00418 Q8N588 |
Accessions | EAW50604 O00418 AK022569 AK308757 AW675420 BC032665 AAH32665 CA397138 DA556486 DA735877 DQ890896 ABM81822 DQ894050 ABM84976 U93850 AAB58270 XR_950786 XR_950787 NM_013302 NP_037434 |
Function | Threonine kinase that regulates protein synthesis by controlling the rate of peptide chain elongation. Upon activation by a variety of upstream kinases including AMPK or TRPM7, phosphorylates the elongation factor EEF2 at a single site, renders it unable to bind ribosomes and thus inactive. In turn, the rate of protein synthesis is reduced. {ECO:0000269|PubMed:14709557, ECO:0000269|PubMed:9144159}. |
Top Pathways | Oxytocin signaling pathway, AMPK signaling pathway |
EEF2K-Over-expression-Lysate - LY13795a from Abgent, a WuXi AppTec company
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EEF2K 293T Cell Transient Overexpression Lysate(Denatured) - H00029904-T01 from Acris Antibodies
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EEF2K overexpression lysate - LY402241 from Acris Antibodies
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EEF2K 293 Cell Lysate - 401968 from ABBIOTEC
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EEF2K Overexpression Lysate (Native) - NBL1-10128 from Novus Biologicals
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eEF2K (h): 293T Lysate - sc-115200 from Santa Cruz Biotechnology
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eEF2K (h2): 293T Lysate - sc-172554 from Santa Cruz Biotechnology
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EEF2K Over-expression Lysate Product - GWB-B70F60 from Genway Biotech
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EEF2K Overexpression Lysate (Denatured) - H00029904-T01 from Novus Biologicals
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Panoply™ Human EEF2K Knockdown Stable Cell Line - CSC-DC004730 from Creative biogene
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Human EEF2K Knockout Cell Line-HeLa - CSC-RT0810 from Creative biogene
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EEF2K KO Cell Lysate-HeLa - CLKO-0313 from Creative biogene
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