FFAR1

Gene Symbol	FFAR1
Entrez Gene	2864
Alt Symbol	FFA1R, GPCR40, GPR40
Species	Human
Gene Type	protein-coding
Description	free fatty acid receptor 1
Other Description	G protein-coupled receptor 40|G-protein coupled receptor 40
Swissprots	O14842 Q4VBL4 Q0VAS2
Accessions	AAB86710 ABY87912 CAD83804 O14842 BC039436 BC095536 AAH95536 BC120943 AAI20944 BC120944 AAI20945 EF611308 ABQ96386 NM_005303 NP_005294
Function	G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose- stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. {ECO:0000250|UniProtKB:Q76JU9, ECO:0000269|PubMed:12496284, ECO:0000269|PubMed:17699519, ECO:0000269|PubMed:24130766}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17699519, ECO:0000269|PubMed:25043059}; Multi-pass membrane protein {ECO:0000269|PubMed:25043059}.
Tissue Specificity	Detected in brain and pancreas. Detected in pancreatic beta cells. {ECO:0000269|PubMed:12496284, ECO:0000269|PubMed:16289108}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-FFAR1-cDNA-Clone - DC14169 from Abgent, a WuXi AppTec company Prices $405.00 Sizes 10 µg Species Human Accession BC120944

Human FFAR1/GPR40 (AAI20945) VersaClone cDNA - RDC0136 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Human FFAR1/GPR40 (NP_005294) VersaClone cDNA - RDC0272 from R&D Systems Prices $199.00 Sizes 10 µg Species Human

Mouse FFAR1/GPR40 (NP_918946) VersaClone cDNA - RDC0516 from R&D Systems Prices $199.00 Sizes 10 µg Species Mouse

FFAR1 - MBS1273374 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC120944

Human FFAR1 ORF clone(NM_005303.2) - CDCL184228 from Creative Biomart Species Human Accession NM_005303.2

Human FFAR1 ORF Clone(NM_005303.2) - CDCL163432 from Creative Biomart Species Human Accession NM_005303.2

Human FFAR1 ORF clone - CDCL107907 from Creative Biomart Species Human Accession NM_005303

Human FFAR1 ORF clone - CDCL107908 from Creative Biomart Species Human Accession NM_005303

Human FFAR1 Gene cDNA clone plasmid - HG13526-G from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13526-NF from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13526-NM from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13526-CF from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13526-ACG from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13526-CM from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13526-NH from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13526-CY from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid - HG13526-UT from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13526-CH from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13526-ACR from Sino Biological Species Human

Human GPCR GPR40/FFAR1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13526-NY from Sino Biological Species Human

Human FFAR1 ORF clone(NM_005303.2) - CDCL184228 from Creative biogene Species Human

Human FFAR1 ORF Clone (BC120944) - CDCS412194 from Creative biogene Species Human Accession O14842

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