FFAR1

Gene Symbol	FFAR1
Entrez Gene	2864
Alt Symbol	FFA1R, GPCR40, GPR40
Species	Human
Gene Type	protein-coding
Description	free fatty acid receptor 1
Other Description	G protein-coupled receptor 40|G-protein coupled receptor 40
Swissprots	O14842 Q4VBL4 Q0VAS2
Accessions	AAB86710 ABY87912 CAD83804 O14842 BC039436 BC095536 AAH95536 BC120943 AAI20944 BC120944 AAI20945 EF611308 ABQ96386 NM_005303 NP_005294
Function	G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose- stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway. {ECO:0000250|UniProtKB:Q76JU9, ECO:0000269|PubMed:12496284, ECO:0000269|PubMed:17699519, ECO:0000269|PubMed:24130766}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:17699519, ECO:0000269|PubMed:25043059}; Multi-pass membrane protein {ECO:0000269|PubMed:25043059}.
Tissue Specificity	Detected in brain and pancreas. Detected in pancreatic beta cells. {ECO:0000269|PubMed:12496284, ECO:0000269|PubMed:16289108}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

GPCR GPR40 peptide (289-300) - ab45737 from Abcam Category Peptide Prices $290.00 Sizes 100 µg Species Human

FFAR1 / GPR40 Antibody Blocking Peptide - LS-E1645 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FFAR1 / GPR40 Blocking Peptide - LS-E10746 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FFAR1 / GPR40 Antibody Blocking Peptide - LS-E25879 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

FFAR1 / GPR40 Antibody Blocking Peptide - LS-E28347 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

FFAR1-Antibody-C-term-Blocking-peptide - BP12402b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

GPR40 blocking peptide - GTX89554-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

FFAR1 Blocking Peptide - 33R-4722 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

GPCR GPR40 Peptide - AC21-0709-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

GPR40 Peptide - 45-694P from ProSci Category Peptide Prices $175.00 Sizes 100 µg Species Human

FFAR1 fusion protein - Ag18545 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human FFAR1, GST-tagged - FFAR1-12852H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Free Fatty Acid Receptor 1 (FFAR1) - RPC971Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Free Fatty Acid Receptor 1 (FFAR1) - RPC971Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

GPR40 (W224) Peptide - BS2793P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Free Fatty Acid Receptor 1 (FFAR1) - RPC971Hu01 from Cloud-clone Category Protein Source E.coli Species Human

GPR40, Peptide - MBS426370 from MyBioSource Category Peptide Prices $175.00 Sizes 100 µg Species Human

GPR40 Blocking Peptide - abx061175 from Abbexa Category Peptide Species Human, Mouse, Rat, Monkey

FFAR1 Peptide, Human - M34GP05683H from Creative Peptides Category Peptide Source Synthetic. Species Human

GPR40 Blocking Peptide - CBP5088 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat, Monkey

Free fatty acid receptor 1 (FFAR1), Recombinant Protein - MBS7014725 from MyBioSource Category Protein Prices $1,110.00, $2,100.00, $3,305.00 Sizes 10 µg, 50 µg, 100 µg Source Cell Free Expression Species Human

Free fatty acid receptor 1 (FFAR1), Recombinant Protein - MBS1101797 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

FFAR1 peptide - orb14118 from Biorbyt Category Peptide Prices $170.00 Sizes 1 mg

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