IL1RN

Gene Symbol IL1RN
Entrez Gene 3557
Alt Symbol DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4
Species Human
Gene Type protein-coding
Description interleukin 1 receptor antagonist
Other Description IL1 inhibitor|IL1RN (IL1F3)|interleukin-1 receptor antagonist protein|intracellular IL-1 receptor antagonist type II|intracellular interleukin-1 receptor antagonist (icIL-1ra)|type II interleukin-1 receptor antagonist
Swissprots Q53SC2 Q14628 P18510 Q9UPC0 Q96GD6 Q7RTZ4 A8K4G1
Accessions AAB41943 AAB92268 AAB92269 AAB92270 AAC13499 AAN87150 AAX93278 CAA03191 CAA03210 CAA45832 CAD29879 CAJ91094 CBY45189 EAW73621 EAW73622 EAW73623 EAW73624 EAW73625 P18510 AF043143 AAC39672 AJ005835 CAA06730 AK290898 BAF83587 AK290926 BAF83615 BC009745 AAH09745 BC068441 BI766516 DQ892566 ABM83492 DQ895781 ABM86707 M55646 AAA59138 X52015 CAA36262 X53296 CAA37386 X84348 CAA59087 XM_005263661 XP_005263718 XM_006712497 XP_006712560 XM_011511121 XP_011509423 NM_000577 NP_000568 NM_173841 NP_776213 NM_173842 NP_776214 NM_173843 NP_776215
Function Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. {ECO:0000269|PubMed:7775431}.
Subcellular Location Isoform 3: Cytoplasm.
Tissue Specificity The intracellular form of IL1RN is predominantly expressed in epithelial cells.

IL-1ra (Interleukin-1ra) Human SimpleStep ELISA™ Kit - ab174450 from Abcam

Category ELISA Kit
Prices $484.00
Sizes 1 x 96 tests
Sensitivity 62 pg/ml
Range 120 pg/ml - 7500 pg/ml
Background-subtracted data values (mean +/- SD) are graphed.

IL-1ra (Interleukin-1ra) Mouse ELISA Kit - ab113348 from Abcam

Category ELISA Kit
Prices $489.00
Sizes 1 x 96 tests
Sensitivity < 2 pg/ml
Range 2.74 pg/ml - 2000 pg/ml
Standard curve of msIL-1Ra in different diluents with background signal subtracted (duplicates; +/- SD).

IL-1RA (Interleukin-1RA antagonist) Human ELISA Kit - ab100565 from Abcam

Category ELISA Kit
Prices $489.00
Sizes 1 x 96 tests
Sensitivity < 0.1 ng/ml
Range 0.124 ng/ml - 30 ng/ml
IL-1Ra measured in lysates from control cells (-) or cells stimulated for 24 hours with 50 ng x mL-1 of PMA (ab120297) with the addition of 1 ug x mL-1 of LPS (Sigma) (P/L) for the last 6 hours (IL-1Ra per mg of extracted protein; duplicates +/- SD).

IL-1RA (Interleukin-1RA antagonist) Human ELISA Kit - ab100564 from Abcam

Category ELISA Kit
Prices $489.00
Sizes 1 x 96 tests
Sensitivity < 0.1 ng/ml
Range 0.124 ng/ml - 30 ng/ml
Representative standard curve using ab100564

Horse IL1RN ELISA Kit (Sandwich ELISA) - LS-F6093 from LifeSpan Bioscience

Category ELISA Kit
Prices $790.00
Sizes 1 plate
Sensitivity 27 pg/ml
Range 31.25-2000 pg/ml

Dog IL1RN ELISA Kit (Sandwich ELISA) - LS-F6092 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 12.7 pg/ml
Range 31.25-2000 pg/ml

Rabbit IL1RN ELISA Kit (Sandwich ELISA) - LS-F6094 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity 3.2 pg/ml
Range 31.25-2000 pg/ml

Rhesus monkey IL1RN ELISA Kit (Sandwich ELISA) - LS-F6098 from LifeSpan Bioscience

Category ELISA Kit
Prices $740.00
Sizes 1 plate
Sensitivity 5.8 pg/ml
Range 31.25-2000 pg/ml

Bovine IL1RN ELISA Kit (Sandwich ELISA) - LS-F6096 from LifeSpan Bioscience

Category ELISA Kit
Prices $780.00
Sizes 1 plate
Sensitivity 31.25 pg/ml
Range 31.25-2000 pg/ml

Mouse IL1RN ELISA Kit (Sandwich ELISA) - LS-F2680 from LifeSpan Bioscience

Category ELISA Kit
Prices $530.00
Sizes 1 plate
Sensitivity 10 pg/ml
Range 31.25-2000 pg/ml

Human IL1RN ELISA Kit (Sandwich ELISA) - LS-F2679 from LifeSpan Bioscience

Category ELISA Kit
Prices $570.00
Sizes 1 plate
Sensitivity 2 pg/ml
Range 31.25-2000 pg/ml

Mouse IL1RN ELISA Kit (Sandwich ELISA) - LS-F4638 from LifeSpan Bioscience

Category ELISA Kit
Prices $470.00
Sizes 1 plate
Sensitivity 1.29 pg/ml
Range 31.25-2000 pg/ml

Human IL1RN ELISA Kit (Sandwich ELISA) - LS-F4639 from LifeSpan Bioscience

Category ELISA Kit
Prices $650.00
Sizes 1 plate
Sensitivity 12.4 pg/ml
Range 31.25-2000 pg/ml

Rat IL1RN ELISA Kit (Sandwich ELISA) - LS-F4640 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity 13.1 pg/ml
Range 31.25-2000 pg/ml

Human IL1RN ELISA Kit (Sandwich ELISA) - LS-F454 from LifeSpan Bioscience

Category ELISA Kit
Prices $460.00, $840.00, $1,960.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity 0.041 ng/ml
Range 31.25-2000 pg/ml

Horse/Equine IL1RN ELISA Kit (Sandwich ELISA) - LS-F421 from LifeSpan Bioscience

Category ELISA Kit
Prices $620.00, $1,090.00, $2,380.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity 12.29 pg/ml
Range 31.25-2000 pg/ml

Mouse IL1RN ELISA Kit (Sandwich ELISA) - LS-F497 from LifeSpan Bioscience

Category ELISA Kit
Prices $460.00, $840.00, $1,960.00
Sizes 1 plate, 2 plate, 5 plate
Sensitivity 2.743 pg/ml
Range 31.25-2000 pg/ml

Human IL1RN ELISA Kit (Sandwich ELISA) - LS-F574 from LifeSpan Bioscience

Category ELISA Kit
Prices $450.00
Sizes 1 plate
Range 31.25-2000 pg/ml

Human IL1RN ELISA Kit (Sandwich ELISA) - LS-F11764 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 0.156
Range 31.25-2000 pg/ml

Pig IL1RN ELISA Kit (Sandwich ELISA) - LS-F11766 from LifeSpan Bioscience

Category ELISA Kit
Prices $700.00
Sizes 1 plate
Sensitivity 0.156
Range 31.25-2000 pg/ml

Rat IL1RN ELISA Kit (Sandwich ELISA) - LS-F11765 from LifeSpan Bioscience

Category ELISA Kit
Prices $600.00
Sizes 1 plate
Sensitivity 31.2
Range 31.25-2000 pg/ml

Human IL-1ra ELISA Kit - RAB0283 from Sigma-Aldrich

Category ELISA Kit
Prices $423.50
Sizes 1 kt
<B>Standard Curve</B><BR/>: Typical Standard Curve for Human IL-1RA ELISA Kit, <B>Cat. No. RAB0283</B>. The standard curve(s) displayed are for demonstration only. A standard curve must be run with each assay.

Human IL-1ra ELISA Kit - RAB0284 from Sigma-Aldrich

Category ELISA Kit
Prices $423.50
Sizes 1 kt
<B>Standard Curve</B><BR/>: Typical Standard Curve for Human IL-1RA ELISA Kit, <B>Cat. No. RAB0284</B>. The standard curve(s) displayed are for demonstration only. A standard curve must be run with each assay.
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