IL1RN

Gene Symbol	IL1RN
Entrez Gene	3557
Alt Symbol	DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4
Species	Human
Gene Type	protein-coding
Description	interleukin 1 receptor antagonist
Other Description	IL1 inhibitor|IL1RN (IL1F3)|interleukin-1 receptor antagonist protein|intracellular IL-1 receptor antagonist type II|intracellular interleukin-1 receptor antagonist (icIL-1ra)|type II interleukin-1 receptor antagonist
Swissprots	Q53SC2 Q14628 P18510 Q9UPC0 Q96GD6 Q7RTZ4 A8K4G1
Accessions	AAB41943 AAB92268 AAB92269 AAB92270 AAC13499 AAN87150 AAX93278 CAA03191 CAA03210 CAA45832 CAD29879 CAJ91094 CBY45189 EAW73621 EAW73622 EAW73623 EAW73624 EAW73625 P18510 AF043143 AAC39672 AJ005835 CAA06730 AK290898 BAF83587 AK290926 BAF83615 BC009745 AAH09745 BC068441 BI766516 DQ892566 ABM83492 DQ895781 ABM86707 M55646 AAA59138 X52015 CAA36262 X53296 CAA37386 X84348 CAA59087 XM_005263661 XP_005263718 XM_006712497 XP_006712560 XM_011511121 XP_011509423 NM_000577 NP_000568 NM_173841 NP_776213 NM_173842 NP_776214 NM_173843 NP_776215
Function	Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2; however, the physiological relevance of the latter association is unsure. {ECO:0000269|PubMed:7775431}.
Subcellular Location	Isoform 3: Cytoplasm.
Tissue Specificity	The intracellular form of IL1RN is predominantly expressed in epithelial cells.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human IL1RA full length protein - ab119745 from Abcam Category Protein Prices $210.00 Sizes 20 µg Source E. coli Species Human

Active human IL1RA full length protein - ab83761 from Abcam Category Protein Prices $340.00 Sizes 5 µg Source HEK 293 cells Species Human

Active human IL1RA full length protein - ab192130 from Abcam Category Protein Prices $192.00 Sizes 100 µg Source E. coli Species Human

Active mouse IL1RA full length protein - ab119723 from Abcam Category Protein Prices $210.00 Sizes 10 µg Source E. coli Species Mouse

Active rat IL1RA full length protein - ab200257 from Abcam Category Protein Prices $107.00 Sizes 10 µg Source E. coli Species Rat

Bottlenose Dolphin IL1RA full length protein - ab169729 from Abcam Category Protein Prices $235.00 Sizes 25 µg Source Yeast Species Dolphin

Chicken IL1RA full length protein - ab169710 from Abcam Category Protein Prices $235.00 Sizes 25 µg Source Yeast Species Chicken

Dog IL1RA protein fragment - ab151198 from Abcam Category Protein Prices $190.00 Sizes 5 µg Source Yeast Species Dog

Human IL1RA full length protein - ab50081 from Abcam Category Protein Source E. coli Species Human

Human IL1RA full length protein - ab51165 from Abcam Category Protein Source E. coli Species Human

Human IL1RA protein fragment - ab53229 from Abcam Category Protein Source E. coli Species Human

IL1RA full length protein - ab151204 from Abcam Category Protein Source Yeast

Pig IL1RA full length protein - ab151205 from Abcam Category Protein Source Yeast Species Pig

Rat IL1RA full length protein - ab201897 from Abcam Category Protein Source E. coli Species Rat

IL1RN Antibody Blocking Peptide - LS-E8238 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

IL1RN Antibody Blocking Peptide - LS-E22994 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IL-1ra/IL-1F3/IL1RN Protein - NBP2-35894 from Novus Biologicals Category Protein Prices $69.00, $169.00, $1,690.00 Sizes 20 µg, 100 µg, 1 mg Source E. coli Species Human

IL-1ra/IL-1F3/IL1RN Recombinant Protein - H00003557-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human IL-1ra/IL-1F3/IL1RN Protein - NBC1-18464 from Novus Biologicals Category Protein Prices $329.00 Sizes 100 µg Source E.coli Species Human

IL-1ra/IL-1F3/IL1RN Recombinant Protein - P4050 from Novus Biologicals Category Protein Prices $369.00 Sizes 20 µg Species Human

IL-1ra/IL-1F3/IL1RN Recombinant Protein - P3628 from Novus Biologicals Category Protein Prices $449.00 Sizes 100 µg Species Human

IL-1ra/IL-1F3/IL1RN Protein - NBP1-99164 from Novus Biologicals Category Protein Species Human

IL-1ra/IL-1F3/IL1RN Protein - NBP1-99441 from Novus Biologicals Category Protein Prices $309.00 Sizes 100 µg Species Human

IL-1ra/IL-1F3/IL1RN Protein - NBP1-99912 from Novus Biologicals Category Protein Prices $379.00 Sizes 50 µg Species Human

IL-1ra/IL-1F3/IL1RN Protein - NBP1-99783 from Novus Biologicals Category Protein Species Human

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