KDM4A

Gene Symbol KDM4A
Entrez Gene 9682
Alt Symbol JHDM3A, JMJD2, JMJD2A, TDRD14A
Species Human
Gene Type protein-coding
Description lysine (K)-specific demethylase 4A
Other Description jmjC domain-containing histone demethylation protein 3A|jumonji C domain-containing histone demethylase 3A|jumonji domain containing 2|jumonji domain containing 2A|jumonji domain-containing protein 2A|lysine-specific demethylase 4A|tudor domain containing 14A
Swissprots O75164 Q5VVB1
Accessions CCQ43452 EAX07085 O75164 AB014577 BAA31652 AK294596 BAG57784 AK300039 BAG61850 AK310295 BC002558 AAH02558 BP198064 CA944984 CN361683 Z70219 XM_005271354 XP_005271411 XM_005271355 XP_005271412 XM_005271356 XP_005271413 XM_011542467 XP_011540769 NM_014663 NP_055478
Function Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959, ECO:0000269|PubMed:16024779}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:15927959}.

JMJD2A (C70G6) Rabbit mAb - 3393 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C70G6
Western blot analysis of extracts from NCCIT, NIH/3T3 and H-4-II-E cells using JMJD2A (C70G6) Rabbit mAb.

JMJD2A (C37E5) Rabbit mAb - 5328 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C37E5
Western blot analysis of extracts from NCCIT and NTERA-2 cell lines using JMJD2A (C37E5) Rabbit mAb.

JMJD2A (D-9) - sc-271210 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JMJD2A (D-9): sc-271210. Western blot analysis of JMJD2A expression in Jurkat (A) and SK-N-MC (B) whole cell lysates.

JMJD2A (D-16) - sc-54623 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

JMJD2A (H-287) - sc-135065 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
JMJD2A (H-287): sc-135065. Western blot analysis of JMJD2A expression in non-transfected (A) and human JMJD2A transfected (B) whole cell lysates.

JMJD2A (H-8) - sc-373850 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
JMJD2A (H-8): sc-373850. Western blot analysis of JMJD2A expression in non-transfected (A) and human JMJD2A transfected (B) whole cell lysates.

JMJD2A (T-18) - sc-54624 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JMJD2A (T-18): sc-54624. Western blot analysis of JMJD2A expression in SK-N-MC (A), Jurkat (B) and NIH/3T3 (C) nuclear extracts.

JMJD2A (3559D5a) - sc-81302 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
JMJD2A (3559D5a): sc-81302 Western Blot analysis of human recombinant JMJD2A fusion protein.

Anti-KDM4A / JHDM3A / JMJD2A antibody - ab106472 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-KDM4A / JHDM3A / JMJD2A antibody (ab106472) at 1 µg/mlLane 2 : Anti-KDM4A / JHDM3A / JMJD2A antibody (ab106472) at 2 µg/mlLane 1 : Rat liver tissue lysateLane 2 : Rat liver tissue lysateLysates/proteins at 15 µg per lane.

Anti-KDM4A / JHDM3A / JMJD2A antibody - ab70785 from Abcam

Prices $378.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human colon carcinoma tissue labelling KDM4A / JHDM3A / JMJD2A at 1/1000 (1µg/ml). Detection: DAB.

Anti-KDM4A / JHDM3A / JMJD2A antibody - ab176199 from Abcam

Prices $378.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KDM4A / JHDM3A / JMJD2A antibody (ab176199) at 1/200 dilutionLane 1 : DLD1 cell lysate at 30 µgLane 2 : DLD1 cell lysate at 60 µg

Anti-KDM4A / JHDM3A / JMJD2A antibody - ab84518 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ab84518, at 1/250 dilution, staining KDM4A / JHDM3A / JMJD2A in formalin-fixed, paraffin-embedded human ovarian tumor by Immunohistochemistry using DAB staining.

Anti-KDM4A / JHDM3A / JMJD2A antibody [13D6] - ChIP Grade - ab105953 from Abcam

Prices $388.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 13D6
Whole cell lysates derived from 293T transfected with Flag-KDM4A were prepared using PBS+1% Triton plus proteinase inhibitor cocktail and used for IP (1 ug). WB was performed using anti-Flag antibody.

Anti-KDM4A / JHDM3A / JMJD2A antibody [3559D5a] - ab54388 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3559D5a

Anti-KDM4A / JHDM3A / JMJD2A antibody [5H1] - ab104831 from Abcam

Host Mouse
Clonality Monoclonal
Clone 5H1
All lanes : Anti-KDM4A / JHDM3A / JMJD2A antibody [5H1] (ab104831) at 1/500 dilutionLane 1 : HEK293 cell lysateLane 2 : KDM4A / JHDM3A / JMJD2A-hIgGFc transfected HEK293 cell lysate

Anti-KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade - ab24545 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-KDM4A / JHDM3A / JMJD2A antibody - ChIP Grade (ab24545) at 1/2000 dilution + HeLa nuclear extract

Anti-KDM4A / JHDM3A / JMJD2A antibody - N-terminal - ab135486 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-KDM4A / JHDM3A / JMJD2A antibody - N-terminal (ab135486) at 1/50 dilutionLane 1 : Non-transfected 293 cell lysateLane 2 : 293 cell lysate transiently transfected the KDM4A / JHDM3A / JMJD2A geneLysates/proteins at 2 µg per lane.

Anti-KDM4A / JHDM3A / JMJD2A Antibody - LS-C71165 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody (aa320-460, Biotin) - LS-C143511 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody (aa320-460, DY650) - LS-C143512 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody (aa320-460, HRP) - LS-C143514 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody (aa320-460, DY488) - LS-C143513 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody (aa320-460, DY550) - LS-C143515 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody - LS-C143950 from LifeSpan Bioscience

Prices $605.00
Sizes 100 µg
Host Sheep
Clonality Polyclonal

Anti-KDM4A / JHDM3A / JMJD2A Antibody (Tyr547, APC) - LS-C236673 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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