KDM4A

Gene Symbol KDM4A
Entrez Gene 9682
Alt Symbol JHDM3A, JMJD2, JMJD2A, TDRD14A
Species Human
Gene Type protein-coding
Description lysine (K)-specific demethylase 4A
Other Description jmjC domain-containing histone demethylation protein 3A|jumonji C domain-containing histone demethylase 3A|jumonji domain containing 2|jumonji domain containing 2A|jumonji domain-containing protein 2A|lysine-specific demethylase 4A|tudor domain containing 14A
Swissprots O75164 Q5VVB1
Accessions CCQ43452 EAX07085 O75164 AB014577 BAA31652 AK294596 BAG57784 AK300039 BAG61850 AK310295 BC002558 AAH02558 BP198064 CA944984 CN361683 Z70219 XM_005271354 XP_005271411 XM_005271355 XP_005271412 XM_005271356 XP_005271413 XM_011542467 XP_011540769 NM_014663 NP_055478
Function Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Subcellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959, ECO:0000269|PubMed:16024779}.
Tissue Specificity Ubiquitous. {ECO:0000269|PubMed:15927959}.

JMJD2A CRISPR/Cas9 KO Plasmid (h) - sc-404599 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A HDR Plasmid (h) - sc-404599-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A Double Nickase Plasmid (h) - sc-404599-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A Double Nickase Plasmid (h2) - sc-404599-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A CRISPR Activation Plasmid (h) - sc-404599-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A CRISPR Activation Plasmid (h2) - sc-404599-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A Lentiviral Activation Particles (h) - sc-404599-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A Lentiviral Activation Particles (h2) - sc-404599-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

JMJD2A siRNA (h) - sc-62515 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD2A shRNA Plasmid (h) - sc-62515-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

JMJD2A shRNA (h) Lentiviral Particles - sc-62515-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A RNAi - H00009682-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU013041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11030 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11030 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR08093 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr08093

KDM4A siRNA (Human) - CRH6454 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human KDM4A (NM_014663.2) - SHH324191 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human JMJD2A(NM_014663.2) - SHL186218 from Creative biogene

Category siRNA
Species Reactivities Human

Human KDM4A siRNA - orb266956 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

KDM4A shRNA Plasmid (Human) - CHH6454 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

KDM4A miRNA 3'UTR clone - MiUTR1H-05068 from Creative biogene

Species Reactivities Human
Search more