KDM4A

Gene Symbol	KDM4A
Entrez Gene	9682
Alt Symbol	JHDM3A, JMJD2, JMJD2A, TDRD14A
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 4A
Other Description	jmjC domain-containing histone demethylation protein 3A|jumonji C domain-containing histone demethylase 3A|jumonji domain containing 2|jumonji domain containing 2A|jumonji domain-containing protein 2A|lysine-specific demethylase 4A|tudor domain containing 14A
Swissprots	O75164 Q5VVB1
Accessions	CCQ43452 EAX07085 O75164 AB014577 BAA31652 AK294596 BAG57784 AK300039 BAG61850 AK310295 BC002558 AAH02558 BP198064 CA944984 CN361683 Z70219 XM_005271354 XP_005271411 XM_005271355 XP_005271412 XM_005271356 XP_005271413 XM_011542467 XP_011540769 NM_014663 NP_055478
Function	Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959, ECO:0000269|PubMed:16024779}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:15927959}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KDM4A / JHDM3A / JMJD2A protein fragment - ab125541 from Abcam Category Protein Source Baculovirus infected sf9 cells Species Human

Human KDM4A / JHDM3A / JMJD2A protein fragment - ab176943 from Abcam Category Protein Source E. coli Species Human

KDM4A / JHDM3A / JMJD2A Antibody Blocking Peptide - LS-E234 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

KDM4A / JHDM3A / JMJD2A Antibody Blocking Peptide - LS-E30766 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

KDM4A / JHDM3A / JMJD2A Antibody Blocking Peptide - LS-E7470 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Peptide - NBP1-77073PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

JMJD2A-Antibody-N-term-Blocking-Peptide - BP1046a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Phospho-JMJD2AY547-Antibody-Blocking-peptide - BP3726a from Abgent, a WuXi AppTec company Category Peptide Prices $120.00 Sizes 100 µg

JMJD2A / KDM4A Control Peptide - AP30460CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

JMJD2A Peptide - 5373P from ProSci Category Peptide Species Human

KDM4A fusion protein - ag20747 from Proteintech Group Category Protein Source E. coli-derived, PET30a Species Human

KDM4A fusion protein - ag13722 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

KDM4A fusion protein - ag13780 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant JMJD2A / KDM4A protein - 31457 from ActiveMotif Category Protein Prices $395.00, $3,500.00 Sizes 20 µg, 1 mg Source Baculovirus Species Human

Recombinant Human KDM4A, GST-tagged - KDM4A-7031H from Creative Biomart Category Protein Source Sf9 Cells Species Human

Recombinant Human KDM4A, GST-tagged - KDM4A-168H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human KDM4A, FLAG-tagged - KDM4A-50H from Creative Biomart Category Protein Source Sf9 insect cells Species Human

Recombinant Lysine Specific Demethylase 4A (KDM4A) - RPG807Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

KDM4A protein-GST fusion - 009-001-S33 from Rockland Immunochemicals Inc Category Protein Prices $499.00 Sizes 50 µg Species Human

KDM4A protein-GST fusion - 009-001-S33S from Rockland Immunochemicals Inc Category Protein Prices $265.00 Sizes 20 µg Species Human

Recombinant Lysine Specific Demethylase 4A (KDM4A) - RPG807Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Pongo abelii Lysine-specific demethylase 4A(KDM4A) ,partial - CSB-YP725425PYX CSB-EP725425PYX CSB-BP725425PYX CSB-MP725425PYX from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Orangutan

Recombinant Human Lysine-specific demethylase 4A(KDM4A) ,partial - CSB-YP012137HU CSB-EP012137HU CSB-BP012137HU CSB-MP012137HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

JMJD2A Tudor Domains (888-1023 aa) (GST-tagged), Human recombinant - 7678-20 from Biovision Category Protein Prices $165.00 Sizes 20 μg Source E. coli Species Human

JMJD2A Tudor Domains (888-1023 aa) (GST-tagged), Human recombinant - 7678-50 from Biovision Category Protein Prices $335.00 Sizes 50 μg Source E. coli Species Human

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