KDM4A

Gene Symbol	KDM4A
Entrez Gene	9682
Alt Symbol	JHDM3A, JMJD2, JMJD2A, TDRD14A
Species	Human
Gene Type	protein-coding
Description	lysine (K)-specific demethylase 4A
Other Description	jmjC domain-containing histone demethylation protein 3A|jumonji C domain-containing histone demethylase 3A|jumonji domain containing 2|jumonji domain containing 2A|jumonji domain-containing protein 2A|lysine-specific demethylase 4A|tudor domain containing 14A
Swissprots	O75164 Q5VVB1
Accessions	CCQ43452 EAX07085 O75164 AB014577 BAA31652 AK294596 BAG57784 AK300039 BAG61850 AK310295 BC002558 AAH02558 BP198064 CA944984 CN361683 Z70219 XM_005271354 XP_005271411 XM_005271355 XP_005271412 XM_005271356 XP_005271413 XM_011542467 XP_011540769 NM_014663 NP_055478
Function	Histone demethylase that specifically demethylates 'Lys- 9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. Demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono- and dimethylated residues. Demethylation of Lys residue generates formaldehyde and succinate. Participates in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
Subcellular Location	Nucleus {ECO:0000255|PROSITE- ProRule:PRU00537, ECO:0000269|PubMed:15927959, ECO:0000269|PubMed:16024779}.
Tissue Specificity	Ubiquitous. {ECO:0000269|PubMed:15927959}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human KDM4A / JHDM3A / JMJD2A ELISA Kit (Sandwich ELISA) - LS-F8937 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 0.126 ng/ml Range 0.313-20 ng/ml

Human KDM4A ELISA Kit - abx152102 from Abbexa Category ELISA Kit Sensitivity 0.126 ng/ml Range 0.313 ng/ml - 20 ng/ml

Lysine Specific Demethylase 4A (KDM4A), Human, ELISA Kit - SEG807Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 0.128ng/mL Range 0.312-20ng/mL

Lysine Specific Demethylase 4A (KDM4A), ELISA Kit - MBS2021779 from MyBioSource Category ELISA Kit Prices $380.00, $565.00, $765.00, $3,130.00, $5,670.00 Sizes 24 -strip-wells, 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity Typically less than 0.126ng/mL. Range 0.313-20ng/mL

ELISA Kit for Lysine Specific Demethylase 4A (KDM4A) - SEG807Hu from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.126ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA’s were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

ELISA Kit for Lysine Specific Demethylase 4A (KDM4A) - SEG807Hu from Cloud-clone Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.126ng/mL. Range 0.313-20ng/mL The standard curve concentrations used for the ELISA's were 20ng/mL, 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL

Lysine Specific Demethylase 4A (KDM4A), Human, ELISA Kit - DL-KDM4A-Hu from ARP American Research Products Category ELISA Kit Prices $655.00 Sizes 96 t Range 0.312-20 ng/mL

Human KDM4A ELISA Kit - abx573008 from Abbexa Category ELISA Kit Sensitivity 0.128 ng/ml Range 0.313 ng/ml - 20 ng/ml

Human KDM4A ELISA Kit - E023202 from Biobool Category ELISA Kit Sensitivity Typically less than 0.126ng/mL.

KDM4A ELISA Kit (Human) (OKCD01012) - OKCD01012 from Aviva Systems Biology Category ELISA Kit Prices $545.00 Sizes 96 wells Sensitivity < 0.126 ng/mL Range 0.312-20 ng/mL

Human Lysine-specific demethylase 4A (KDM4A) ELISA Kit - AE37029HU from ARP American Research Products Category ELISA Kit Prices $549.00 Sizes 96 t Sensitivity 0.126 ng/mL Range 0.312-20 ng/mL

Lysine Specific Demethylase 4A (KDM4A), ELISA Kit - MBS453977 from MyBioSource Category ELISA Kit Prices $415.00, $550.00, $2,425.00, $4,710.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity <0.128ng/mL Range 0.312-20ng/mL

Lysine-Specific Demethylase 4A (KDM4A), ELISA Kit - MBS9380482 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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