LNX1

Gene Symbol	LNX1
Entrez Gene	84708
Alt Symbol	LNX, MPDZ, PDZRN2
Species	Human
Gene Type	protein-coding
Description	ligand of numb-protein X 1, E3 ubiquitin protein ligase
Other Description	E3 ubiquitin-protein ligase LNX|PDZ domain-containing ring finger protein 2|multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX|numb-binding protein 1
Swissprots	Q8N4C2 Q9BY20 Q8TBB1 Q96MJ7 Q4W5K7
Accessions	AAY41000 EAX05450 EAX05451 Q8TBB1 AF237782 AAK15039 AK056823 BAB71291 AK294611 BAG57796 AY358326 AAQ88692 BC022983 AAH22983 BC034737 AAH34737 BC094772 DA154083 DA625539 DA854815 DA874715 DB159390 DQ893984 ABM84910 XM_005265785 XP_005265842 XM_005265786 XP_005265843 NM_001126328 NP_001119800 NM_032622 NP_116011
Function	E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity). {ECO:0000250}.
Subcellular Location	Cytoplasm {ECO:0000250}.
Tissue Specificity	Expressed in heart, placenta, kidney, pancreas and brain. {ECO:0000269|PubMed:11521506}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LNX1 Gene cDNA Clone - orb144103 from Biorbyt Prices $366.00 Sizes 10 μg Species Human

Human-LNX1-cDNA-Clone - DC06788 from Abgent, a WuXi AppTec company Prices $982.80 Sizes 10 µg Species Human Accession BC022983

LNX1 - MBS1268227 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC022983

LNX1 - MBS1273248 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC034737

Human LNX1 ORF Clone(NM_032622.2) - CDCL168779 from Creative Biomart Species Human Accession NM_032622.2

Human LNX1 ORF Clone(NM_001126328.2) - CDCL168780 from Creative Biomart Species Human Accession NM_001126328.2

Human LNX1 ORF Clone(NM_001126328.2) - CDCR348334 from Creative Biomart Species Human Accession NM_001126328.2

Human LNX1 ORF Clone(NM_001126328.2) - CDCR348335 from Creative Biomart Species Human Accession NM_001126328.2

Human LNX1 Gene ORF cDNA clone in cloning vector - HG13586-G from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, N-His tag - HG13586-NH from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13586-CY from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, C-His tag - HG13586-CH from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid - HG13586-UT from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13586-ACR from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, N-OFPSpark tag - HG13586-ANR from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13586-NY from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13586-ACG from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13586-NF from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, N-GFPSpark tag - HG13586-ANG from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13586-NM from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13586-CF from Sino Biological Species Human

Human LNX1 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13586-CM from Sino Biological Species Human

Human LNX1 ORF Clone(NM_001126328.2) - CDCR348334 from Creative biogene Species Human

Human LNX1 ORF Clone (BC022983) - CDCS407756 from Creative biogene Species Human Accession Q8TBB1

Human LNX1 ORF Clone (BC034737) - CDCS407757 from Creative biogene Species Human Accession Q8TBB1

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