LNX1

Gene Symbol LNX1
Entrez Gene 84708
Alt Symbol LNX, MPDZ, PDZRN2
Species Human
Gene Type protein-coding
Description ligand of numb-protein X 1, E3 ubiquitin protein ligase
Other Description E3 ubiquitin-protein ligase LNX|PDZ domain-containing ring finger protein 2|multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX|numb-binding protein 1
Swissprots Q8N4C2 Q9BY20 Q8TBB1 Q96MJ7 Q4W5K7
Accessions AAY41000 EAX05450 EAX05451 Q8TBB1 AF237782 AAK15039 AK056823 BAB71291 AK294611 BAG57796 AY358326 AAQ88692 BC022983 AAH22983 BC034737 AAH34737 BC094772 DA154083 DA625539 DA854815 DA874715 DB159390 DQ893984 ABM84910 XM_005265785 XP_005265842 XM_005265786 XP_005265843 NM_001126328 NP_001119800 NM_032622 NP_116011
Function E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of NUMB. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates ubiquitination of isoform p66 and isoform p72 of NUMB, but not that of isoform p71 or isoform p65 (By similarity). {ECO:0000250}.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Expressed in heart, placenta, kidney, pancreas and brain. {ECO:0000269|PubMed:11521506}.

LNX1 CRISPR/Cas9 KO Plasmid (h) - sc-408300 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 HDR Plasmid (h) - sc-408300-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 Double Nickase Plasmid (h) - sc-408300-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 Double Nickase Plasmid (h2) - sc-408300-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 CRISPR Activation Plasmid (h) - sc-408300-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 CRISPR Activation Plasmid (h2) - sc-408300-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 Lentiviral Activation Particles (h) - sc-408300-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 Lentiviral Activation Particles (h2) - sc-408300-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LNX1 siRNA (h) - sc-60956 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LNX1 shRNA Plasmid (h) - sc-60956-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LNX1 shRNA (h) Lentiviral Particles - sc-60956-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU134861 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN11787 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11787 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10018 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10018

LNX1 siRNA (Human) - CRJ3597 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Lnx1 RNAi - H00084708-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human LNX1 (NM_032622.2) - SHH331199 from Creative biogene

Category siRNA
Species Reactivities Human

Human LNX1 siRNA - orb274098 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

LNX1 shRNA Plasmid (Human) - CHJ3597 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LNX1 miRNA 3'UTR clone - MiUTR3H-10775 from Creative biogene

Species Reactivities Human

LNX1 miRNA 3'UTR clone - MiUTR3H-10776 from Creative biogene

Species Reactivities Human
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