SUPV3L1

Gene Symbol SUPV3L1
Entrez Gene 6832
Alt Symbol SUV3
Species Human
Gene Type protein-coding
Description suppressor of var1, 3-like 1 (S. cerevisiae)
Other Description ATP-dependent RNA helicase SUPV3L1, mitochondrial|SUV3-like protein 1|suppressor of var1, 3-like 1(SUV3)
Swissprots A8K301 Q8IYB8 O43630
Accessions EAW54314 EAW54315 Q8IYB8 AF042169 AAB97370 AK290416 BAF83105 AK299670 BAH13097 BC036112 AAH36112 BM675613 DC398467 DQ891004 ABM81930 DQ894183 ABM85109 XM_011540106 XP_011538408 XM_011540107 XP_011538409 NM_001301683 NP_001288612 NM_003171 NP_003162
Function Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. {ECO:0000269|PubMed:12466530, ECO:0000269|PubMed:15096047, ECO:0000269|PubMed:17352692, ECO:0000269|PubMed:17961633, ECO:0000269|PubMed:18678873, ECO:0000269|PubMed:19509288, ECO:0000269|PubMed:19864255}.
Subcellular Location Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Tissue Specificity Broadly expressed. {ECO:0000269|PubMed:10453991}.

SUPV3L1 293T Cell Transient Overexpression Lysate(Denatured) - H00006832-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

SUPV3L1 overexpression lysate - LY418860 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

SUV3L1 Overexpression Lysate (Denatured) - H00006832-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
SUPV3L1 transfected lysate.

SUV3L1 Overexpression Lysate (Native) - NBP2-10874 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: SUV3L1 Overexpression Lysate (Adult Normal) [NBP2-10874] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for SUV3L1.

Panoply™ Human SUPV3L1 Knockdown Stable Cell Line - CSC-DC015418 from Creative biogene

Category Cell Line
Species Human
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