SUPV3L1

Gene Symbol	SUPV3L1
Entrez Gene	6832
Alt Symbol	SUV3
Species	Human
Gene Type	protein-coding
Description	suppressor of var1, 3-like 1 (S. cerevisiae)
Other Description	ATP-dependent RNA helicase SUPV3L1, mitochondrial|SUV3-like protein 1|suppressor of var1, 3-like 1(SUV3)
Swissprots	A8K301 Q8IYB8 O43630
Accessions	EAW54314 EAW54315 Q8IYB8 AF042169 AAB97370 AK290416 BAF83105 AK299670 BAH13097 BC036112 AAH36112 BM675613 DC398467 DQ891004 ABM81930 DQ894183 ABM85109 XM_011540106 XP_011538408 XM_011540107 XP_011538409 NM_001301683 NP_001288612 NM_003171 NP_003162
Function	Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. {ECO:0000269|PubMed:12466530, ECO:0000269|PubMed:15096047, ECO:0000269|PubMed:17352692, ECO:0000269|PubMed:17961633, ECO:0000269|PubMed:18678873, ECO:0000269|PubMed:19509288, ECO:0000269|PubMed:19864255}.
Subcellular Location	Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Tissue Specificity	Broadly expressed. {ECO:0000269|PubMed:10453991}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SUV3L1 protein fragment - ab159614 from Abcam Category Protein Source Wheat germ Species Human

SUPV3L1 Antibody Blocking Peptide - LS-E13013 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human SUV3L1 Protein - H00006832-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

SUPV3L1 Blocking Peptide - 33R-7571 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

SUPV3L1 - H00006832-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

SUPV3L1 - H00006832-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

SUPV3L1 fusion protein - Ag3542 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

SUPV3L1 fusion protein - Ag8308 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human SUPV3L1, GST-tagged - SUPV3L1-3059H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human ATP-dependent RNA helicase SUPV3L1, mitochondrial(SUPV3L1) - CSB-YP814232HU CSB-EP814232HU CSB-BP814232HU CSB-MP814232HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

SUPV3L1 - TP306350 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

ATP-dependent RNA helicase SUPV3L1, mitochondrial (SUPV3L1) , Recombinant Protein - MBS1437214 from MyBioSource Category Protein Prices $2,725.00, $2,725.00, $3,145.00, $3,145.00 Sizes 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

SUV3L1 Recombinant Protein Antigen - NBP2-34047PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SUV3L1 Recombinant Protein Antigen - NBP1-80711PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SUPV3L1-Antibody-N-term-Blocking-Peptide - BP9772a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SUPV3L1 Peptide, Human - M34GP15418H from Creative Peptides Category Peptide Source Synthetic. Species Human

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