SUPV3L1

Gene Symbol SUPV3L1
Entrez Gene 6832
Alt Symbol SUV3
Species Human
Gene Type protein-coding
Description suppressor of var1, 3-like 1 (S. cerevisiae)
Other Description ATP-dependent RNA helicase SUPV3L1, mitochondrial|SUV3-like protein 1|suppressor of var1, 3-like 1(SUV3)
Swissprots A8K301 Q8IYB8 O43630
Accessions EAW54314 EAW54315 Q8IYB8 AF042169 AAB97370 AK290416 BAF83105 AK299670 BAH13097 BC036112 AAH36112 BM675613 DC398467 DQ891004 ABM81930 DQ894183 ABM85109 XM_011540106 XP_011538408 XM_011540107 XP_011538409 NM_001301683 NP_001288612 NM_003171 NP_003162
Function Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3' overhang double-stranded RNA with a 3'-to-5' directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double-stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5'-to-3' direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of non coding processing intermediates. Also implicated in recombination and chromatin maintenance pathways. May protect cells from apoptosis. Associates with mitochondrial DNA. {ECO:0000269|PubMed:12466530, ECO:0000269|PubMed:15096047, ECO:0000269|PubMed:17352692, ECO:0000269|PubMed:17961633, ECO:0000269|PubMed:18678873, ECO:0000269|PubMed:19509288, ECO:0000269|PubMed:19864255}.
Subcellular Location Nucleus. Mitochondrion matrix. Mitochondrion matrix, mitochondrion nucleoid.
Tissue Specificity Broadly expressed. {ECO:0000269|PubMed:10453991}.

SUV3 (E-1) - sc-365750 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
SUV3 (E-1): sc-365750. Western blot analysis of SUV3 expression in A-431 (A) and LNCaP (B) whole cell lysates.

SUV3 (E-14) - sc-107090 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

SUV3 (H-180) - sc-135224 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

SUV3 (K-13) - sc-107091 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-SUV3L1 antibody - ab176854 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-SUV3L1 antibody (ab176854) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : HeLa whole cell lysate at 5 µgLane 4 : 293T whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-SUV3L1 antibody - ab85598 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-SUV3L1 antibody (ab85598) at 1 µg/ml (in 5% skim milk / PBS buffer) + Fetal muscle lysate (Human) at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-SUV3L1 antibody - ab127909 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-SUV3L1 antibody (ab127909) at 1/1000 dilution + PC3 whole cell lysate at 30 µgdeveloped using the ECL technique

Anti-SUV3L1 antibody - ab72623 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-SUV3L1 antibody (ab72623) at 1/500 dilution + human pancreas tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-SUV3L1 antibody [GT244] - ab184612 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone GT244
All lanes : Anti-SUV3L1 antibody [GT244] (ab184612) at 1/5000 dilutionLane 1 : HeLa whole cell lysate extractLane 2 : GFP-Human SUV3L1-transfected HeLa whole cell lysate extractLysates/proteins at 30 µg per lane.

Anti-SUPV3L1 Antibody (aa72-121) - LS-C101626 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
SUPV3L1 antibody LS-C101626 Western blot of Fetal Muscle lysate.

Anti-SUPV3L1 Antibody (aa686-736) - LS-C289756 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SUPV3L1 Antibody (aa736-786) - LS-C289757 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUV3L1 Antibody - NBP2-20539 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SUV3L1 Antibody [NBP2-20539] - Upper panel: SUPV3L1 antibody [C2C3], C-term Lower panel: beta Actin antibody A. 30 ug HeLa whole cell lysate/extract B. 30 ug whole cell lysate/extract of SUPV3L1 shRNA-tran

SUV3L1 Antibody - NBP2-34047 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SUV3L1 Antibody [NBP2-34047] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

SUV3L1 Antibody - H00006832-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

SUV3L1 Antibody - NBP1-71813 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUV3L1 Antibody - NBP1-71812 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-SUPV3L1 antibody produced in rabbit - SAB2102339 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-SUPV3L1: <B>Cat. No.SAB2102339</B>: SUPV3L1 in Fetal Muscle tissue lysate with SUPV3L1 antibody at 1.0 μg/mL.

Anti-SUPV3L1 antibody produced in mouse - SAB1400271 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-SUPV3L1, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400271</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~88 kDa using human pancreas lysate.

Anti-SUPV3L1 antibody produced in rabbit - HPA038405 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SUPV3L1: <B>Cat. No. HPA038405</B>: Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells in seminiferus ducts.

Anti-SUPV3L1 antibody produced in rabbit - HPA038380 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-SUPV3L1: <B>Cat. No. HPA038380</B>: Immunohistochemical staining of Human testis shows strong cytoplasmic positivity in Leydig cells.

SUPV3L1 antibody - N-terminal region (ARP36353_P050) - ARP36353_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

SUPV3L1-Antibody-N-term - AP9772a from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of lysates from SW620, PC-3 cell line, mouse kidney, rat kidney tissue lysate (from left to right), using SUPV3L1 Antibody (N-term)(Cat. #AP9772a). AP9772a was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

SUPV3L1 antibody - 70R-4616 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

SUPV3L1 Antibody - abx034507 from Abbexa

Host Rabbit
Clonality Polyclonal
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