Gene Symbol | UGT1A7 |
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Entrez Gene | 54577 |
Alt Symbol | UDPGT, UDPGT 1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G |
Species | Human |
Gene Type | protein-coding |
Description | UDP glucuronosyltransferase 1 family, polypeptide A7 |
Other Description | UDP glycosyltransferase 1 family, polypeptide A7|UDP-glucuronosyltransferase 1 family polypeptide A7s|UDP-glucuronosyltransferase 1-7|UDP-glucuronosyltransferase 1-G|UDP-glucuronosyltransferase 1A7 |
Swissprots | Q9HAW7 O00473 B8K293 |
Accessions | AAA80548 AAG30419 AAG43194 AAG43195 AAG43196 AAK97173 AAK97174 AAK97175 AAQ04300 AAQ04301 AAQ04478 AAQ04806 AAQ07456 CAL32687 Q9HAW7 AY435142 AAR95643 BC001521 AAH01521 BC146418 AAI46419 BC153172 AAI53173 DQ383513 ABD42926 U89507 AAB81536 NM_019077 NP_061950 |
Function | UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. Isoform 2 lacks transferase activity but acts as a negative regulator of isoform 1. {ECO:0000269|PubMed:23360619}. |
Subcellular Location | Microsome. Endoplasmic reticulum membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
Tissue Specificity | Liver and gastric tissue. Isoform 1 and isoform 2 are expressed in esophagus. Neither isoform is expressed in liver, kidney, colon and small intestine (PubMed:18004212). {ECO:0000269|PubMed:18004212, ECO:0000269|PubMed:9271343}. |
Top Pathways | Chemical carcinogenesis, Steroid hormone biosynthesis, Drug metabolism - other enzymes, Drug metabolism - cytochrome P450, Metabolism of xenobiotics by cytochrome P450 |
Anti-UGT1A7 antibody - ab105685 from Abcam
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Anti-UGT1A7 antibody - ab169574 from Abcam
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Anti-UGT1A7 Antibody (aa74-123) - LS-C81383 from LifeSpan Bioscience
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UGT1A7 Antibody - NBP1-91335 from Novus Biologicals
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UGT1A7 Antibody - H00054577-B01P-50ug from Novus Biologicals
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Anti-UGT1A7 antibody produced in mouse - SAB1412844 from Sigma-Aldrich
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Anti-UGT1A7 antibody produced in rabbit - SAB2102642 from Sigma-Aldrich
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UGT1A7 antibody - N-terminal region (ARP49438_P050) - ARP49438_P050 from Aviva Systems Biology
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UGT1A7 antibody - 70R-7305 from Fitzgerald
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UGT1A7 antibody - H00054577-B01P from Acris Antibodies
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UGT1A7 Antibody - GWB-MR503H from Genway Biotech
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Anti-UGT1A7 monoclonal antibody - DCABH-13917 from Creative Diagnostics
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Anti-UGT1A7 (full length) polyclonal antibody - DPABH-08151 from Creative Diagnostics
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UGT1A7-antibody-N-terminal-region-AI13023 - AI13023 from Abgent, a WuXi AppTec company
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UGT1A7, Polyclonal Antibody - MBS5303032 from MyBioSource
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UGT1A7 antibody - TA331082 from Acris Antibodies
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UGT1A7 antibody - orb313418 from Biorbyt
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Anti-UGT1A7 Antibody A03384 - A03384 from Boster Bio
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UGT1A7 antibody - N-terminal region : Biotin (ARP49438_P050-Biotin) - ARP49438_P050-Biotin from Aviva Systems Biology
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UGT1A7 antibody - N-terminal region : FITC (ARP49438_P050-FITC) - ARP49438_P050-FITC from Aviva Systems Biology
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UGT1A7 antibody - N-terminal region : HRP (ARP49438_P050-HRP) - ARP49438_P050-HRP from Aviva Systems Biology
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Anti-UGT1A7 Antibody (aa74-123, HRP) - LS-C452346 from LifeSpan Bioscience
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Anti-UGT1A7 Antibody (aa74-123, FITC) - LS-C452345 from LifeSpan Bioscience
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Anti-UGT1A7 Antibody (aa74-123, Biotin) - LS-C451849 from LifeSpan Bioscience
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