FNTA

Gene Symbol FNTA
Entrez Gene 2339
Alt Symbol FPTA, PGGT1A, PTAR2
Species Human
Gene Type protein-coding
Description farnesyltransferase, CAAX box, alpha
Other Description FTase-alpha|GGTase-I-alpha|farnesyl-protein transferase alpha-subunit|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha|protein prenyltransferase alpha subunit repeat containing 2|ras proteins prenyltransferase subunit alpha|type I protein geranyl-geranyltransferase alpha subunit
Swissprots Q9UDC1 A6NJW0 Q53XJ9 P49354
Accessions AAB26814 EAW63188 EAW63189 EAW63190 EAW63191 EAW63192 P49354 AB209689 BAD92926 AK091717 AK123002 BAG53844 AK292121 BAF84810 AL698961 BC017029 AAH17029 BC037295 BC084566 AAH84566 BI913631 BM686906 BT009854 AAP88856 BX648381 L00634 AAA35853 L10413 AAA86285 NM_002027 NP_002018 NR_033698 NM_001018676 NM_001018677
Function Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. {ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:16893176, ECO:0000269|PubMed:19246009, ECO:0000269|PubMed:8419339, ECO:0000269|PubMed:8494894}.
Top Pathways Terpenoid backbone biosynthesis

FTα (B-1) - sc-390757 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FTα (B-1): sc-390757. Western blot analysis of FTα expression in non-transfected: sc-117752 (A) and mouse FTα transfected: sc-120327 (B) 293T whole cell lysates.

FTα (D-5) - sc-374262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FTα (D-5): sc-374262. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

FTα (C-19) - sc-487 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FTα (C-19): sc-487. Western blot analysis of FTα expression in non-transfected: sc-117752 (A) and human FTα transfected: sc-158523 (B) 293T whole cell lysates.

FTα (C-4) - sc-373749 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FTα (C-4): sc-373749. Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic staining of glandular cells.

FTα (47) - sc-136306 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FTYα (47): sc-136306. Western blot analysis of FTα expression in rat pituitary tissue extract.

FTα (FL-379) - sc-13964 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FTα (FL-379): sc-13964. Immunofluorescence staining of methanol-fixed HeLa cells showing perinuclear localization.

FTα (IB7) - sc-23906 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
FTα (IB7): sc-23906. Western blot analysis of FTα expression in non-transfected 293T: sc-117752 (A), human FTα transfected 293T: sc-158523 (B) and A-431 (C) whole cell lysates.

FTα (Y-53) - sc-136 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
FTα (Y-53): sc-136. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing cytoplasmic and nuclear staining of cells in seminiferous ducts and Leydig cells.

Anti-FNTA antibody - ab38448 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-FNTA antibody (ab38448) at 1/100 dilution + Mouse brain tissue lysate

Anti-FNTA antibody [EPR4704] - ab109738 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4704
All lanes : Anti-FNTA antibody [EPR4704] (ab109738) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : HeLa cell lysateLane 3 : JAR cell lysateLysates/proteins at 10 µg per lane.

Anti-FNTA antibody - C-terminal - ab186136 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Detection of FNTA in Immunoprecipitates of 293T whole cell lysates (1 mg for IP, 20% of IP loaded) using ab186136 at 6 µg per reaction for IP (Lane 1). For WB detection, ab186136 was used at 1µg/ml. Lane 2 Control IgG IP. Detection: Chemiluminescence with an exposure time of 30 seconds.

Anti-PTAR2 / FNTA Antibody - LS-C36310 from LifeSpan Bioscience

Prices $455.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-PTAR2 / FNTA Antibody (aa52-79, AP) - LS-C259410 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (aa52-79, APC) - LS-C259411 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (aa52-79, Biotin) - LS-C259412 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (aa52-79, FITC) - LS-C259413 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (aa52-79, Azide-free, HRP) - LS-C259414 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (aa52-79, PE) - LS-C259415 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (Internal, AP) - LS-C277287 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (Internal, APC) - LS-C277288 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (Internal, Biotin) - LS-C277289 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (N-Terminus) - LS-C107686 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
FNTA antibody LS-C107686 Western blot of THP-1 cell lysate.

Anti-PTAR2 / FNTA Antibody (C-Terminus) - LS-C81251 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-PTAR2 / FNTA Antibody (Internal, FITC) - LS-C277290 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PTAR2 / FNTA Antibody (Internal, Azide-free, HRP) - LS-C277291 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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