Gene Symbol | FNTA |
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Entrez Gene | 2339 |
Alt Symbol | FPTA, PGGT1A, PTAR2 |
Species | Human |
Gene Type | protein-coding |
Description | farnesyltransferase, CAAX box, alpha |
Other Description | FTase-alpha|GGTase-I-alpha|farnesyl-protein transferase alpha-subunit|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha|protein prenyltransferase alpha subunit repeat containing 2|ras proteins prenyltransferase subunit alpha|type I protein geranyl-geranyltransferase alpha subunit |
Swissprots | Q9UDC1 A6NJW0 Q53XJ9 P49354 |
Accessions | AAB26814 EAW63188 EAW63189 EAW63190 EAW63191 EAW63192 P49354 AB209689 BAD92926 AK091717 AK123002 BAG53844 AK292121 BAF84810 AL698961 BC017029 AAH17029 BC037295 BC084566 AAH84566 BI913631 BM686906 BT009854 AAP88856 BX648381 L00634 AAA35853 L10413 AAA86285 NM_002027 NP_002018 NR_033698 NM_001018676 NM_001018677 |
Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. {ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:16893176, ECO:0000269|PubMed:19246009, ECO:0000269|PubMed:8419339, ECO:0000269|PubMed:8494894}. |
Top Pathways | Terpenoid backbone biosynthesis |
Human FNTA full length protein - ab158460 from Abcam
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PTAR2 / FNTA Antibody Blocking Peptide - LS-E5528 from LifeSpan Bioscience
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PTAR2 / FNTA Antibody Blocking Peptide - LS-E17552 from LifeSpan Bioscience
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PTAR2 / FNTA Antibody Blocking Peptide - LS-E17553 from LifeSpan Bioscience
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PTAR2 / FNTA Antibody Blocking Peptide - LS-E6964 from LifeSpan Bioscience
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FNTA Recombinant Protein - H00002339-P01 from Novus Biologicals
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FNTA Peptide - P1103 from Novus Biologicals
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FNTA-Antibody-N-term-Blocking-Peptide - BP18056a from Abgent, a WuXi AppTec company
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FNTA-Antibody-Center-Blocking-Peptide - BP2420a from Abgent, a WuXi AppTec company
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FNTA Blocking Peptide - 33R-2083 from Fitzgerald
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FNTA Blocking Peptide - 33R-5613 from Fitzgerald
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FNTA - H00002339-P01-10 from Acris Antibodies
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FNTA - H00002339-P01-25 from Acris Antibodies
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FNTA fusion protein - Ag2918 from Proteintech Group
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Recombinant Human FNTA, GST-tagged - FNTA-12959H from Creative Biomart
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Recombinant Farnesyltransferase Alpha (FNTa) - RPG487Hu01 from Uscn Life Science Inc.
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Recombinant Farnesyltransferase Alpha (FNTa) - RPG487Hu01 from Cloud-clone
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Recombinant Human Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha(FNTA) - CSB-YP008777HU CSB-EP008777HU CSB-BP008777HU CSB-MP008777HU from Cusabio
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FNTA (transcript variant 1) - TP310293 from Acris Antibodies
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FNTA Recombinant Protein Antigen - NBP1-83428PEP from Novus Biologicals
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FNTA-Antibody-C-term-Blocking-Peptide - BP2420b from Abgent, a WuXi AppTec company
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FNTA Peptide, Human - M34GP05821H from Creative Peptides
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FNTA Recombinant Protein (OPCD03284) - OPCD03284 from Aviva Systems Biology
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Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha (FNTA), Recombinant Protein - MBS959909 from MyBioSource
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