Gene Symbol | FNTA |
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Entrez Gene | 2339 |
Alt Symbol | FPTA, PGGT1A, PTAR2 |
Species | Human |
Gene Type | protein-coding |
Description | farnesyltransferase, CAAX box, alpha |
Other Description | FTase-alpha|GGTase-I-alpha|farnesyl-protein transferase alpha-subunit|protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha|protein prenyltransferase alpha subunit repeat containing 2|ras proteins prenyltransferase subunit alpha|type I protein geranyl-geranyltransferase alpha subunit |
Swissprots | Q9UDC1 A6NJW0 Q53XJ9 P49354 |
Accessions | AAB26814 EAW63188 EAW63189 EAW63190 EAW63191 EAW63192 P49354 AB209689 BAD92926 AK091717 AK123002 BAG53844 AK292121 BAF84810 AL698961 BC017029 AAH17029 BC037295 BC084566 AAH84566 BI913631 BM686906 BT009854 AAP88856 BX648381 L00634 AAA35853 L10413 AAA86285 NM_002027 NP_002018 NR_033698 NM_001018676 NM_001018677 |
Function | Essential subunit of both the farnesyltransferase and the geranylgeranyltransferase complex. Contributes to the transfer of a farnesyl or geranylgeranyl moiety from farnesyl or geranylgeranyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X. May positively regulate neuromuscular junction development downstream of MUSK via its function in RAC1 prenylation and activation. {ECO:0000269|PubMed:12036349, ECO:0000269|PubMed:12825937, ECO:0000269|PubMed:16893176, ECO:0000269|PubMed:19246009, ECO:0000269|PubMed:8419339, ECO:0000269|PubMed:8494894}. |
Top Pathways | Terpenoid backbone biosynthesis |
Human-FNTA-cDNA-Clone - DC09016 from Abgent, a WuXi AppTec company
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FNTA - MBS1277458 from MyBioSource
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FNTA - MBS1275171 from MyBioSource
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Human FNTA cDNA clone(NM_002027.2) - CDFH007023 from Creative Biomart
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Mouse FNTA ORF clone - CDCL109041 from Creative Biomart
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Mouse FNTA ORF clone - CDCL109042 from Creative Biomart
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Human FNTA ORF clone - CDCL109043 from Creative Biomart
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Human FNTA ORF clone - CDCL109044 from Creative Biomart
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Human FNTA ORF Clone(NM_002027.2) - CDCL163888 from Creative Biomart
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Human FNTA ORF Clone(NM_002027.2) - CDCL163889 from Creative Biomart
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Human FNTA ORF Clone(NM_002027.2) - CDCR282191 from Creative Biomart
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Human FNTA ORF Clone(NM_002027.2) - CDCR282192 from Creative Biomart
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Human FNTA ORF Clone(NM_002027.2) - CDCR282191 from Creative biogene
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Human FNTA ORF Clone (BC037295) - CDCS410564 from Creative biogene
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Human FNTA ORF Clone (BC084566) - CDCS410565 from Creative biogene
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Human FNTA cDNA Clone(NM_002027.2) - CDFH007023 from Creative biogene
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