MSL2

Gene Symbol	MSL2
Entrez Gene	55167
Alt Symbol	MSL-2, MSL2L1, RNF184
Species	Human
Gene Type	protein-coding
Description	male-specific lethal 2 homolog (Drosophila)
Other Description	E3 ubiquitin-protein ligase MSL2|MSL2-like 1|male-specific lethal 2-like 1|male-specific lethal-2 homolog 1|ring finger protein 184
Swissprots	Q9NVS4 G5E9I1 Q8NDB4 Q9HCI7 Q0D2P1 B4DYL4
Accessions	EAW79119 EAW79120 Q9HCI7 AB046805 BAB13411 AK001408 BAA91673 AK091956 AK292557 BAF85246 AK302491 BAG63776 AL834289 CAD38963 AW237818 AW271295 BC032719 AAH32719 BC093764 AAH93764 BC093790 AAH93790 DA674784 DC409643 XM_005247571 XP_005247628 XM_005247572 XP_005247629 XM_006713684 XP_006713747 XM_011512949 XP_011511251 NM_001145417 NP_001138889 NM_018133 NP_060603
Function	Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. {ECO:0000269|PubMed:21726816}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

MSL2L1 293T Cell Transient Overexpression Lysate(Denatured) - H00055167-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

MSL2 overexpression lysate - LY428876 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

MSL2 293 Cell Lysate - 406436 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg Species Drosophila

MSL2L1 Overexpression Lysate (Denatured) - H00055167-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

MSL2L1 Overexpression Lysate (Native) - NBL1-13330 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

MSL2 Over-expression Lysate Product - GWB-4665C4 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

MSL2L1 Overexpression Lysate (Denatured) - H00055167-T02 from Novus Biologicals Category Cell Lysate Prices $299.00 Sizes 100 µl

Panoply™ Human MSL2 Knockdown Stable Cell Line - CSC-DC009827 from Creative biogene Category Cell Line Species Human

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