MSL2

Gene Symbol MSL2
Entrez Gene 55167
Alt Symbol MSL-2, MSL2L1, RNF184
Species Human
Gene Type protein-coding
Description male-specific lethal 2 homolog (Drosophila)
Other Description E3 ubiquitin-protein ligase MSL2|MSL2-like 1|male-specific lethal 2-like 1|male-specific lethal-2 homolog 1|ring finger protein 184
Swissprots Q9NVS4 G5E9I1 Q8NDB4 Q9HCI7 Q0D2P1 B4DYL4
Accessions EAW79119 EAW79120 Q9HCI7 AB046805 BAB13411 AK001408 BAA91673 AK091956 AK292557 BAF85246 AK302491 BAG63776 AL834289 CAD38963 AW237818 AW271295 BC032719 AAH32719 BC093764 AAH93764 BC093790 AAH93790 DA674784 DC409643 XM_005247571 XP_005247628 XM_005247572 XP_005247629 XM_006713684 XP_006713747 XM_011512949 XP_011511251 NM_001145417 NP_001138889 NM_018133 NP_060603
Function Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. {ECO:0000269|PubMed:21726816}.

RNF184 (N-13) - sc-103156 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RNF184 (N-13): sc-103156. Western blot analysis of RNF184 expression in mouse brain tissue extract.

RNF184 (D-17) - sc-103155 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MSL2L1 antibody - ab67379 from Abcam

Prices $370.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
All lanes : Anti-MSL2L1 antibody (ab67379) at 1/500 dilutionLane 1 : MSL2L1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-MSL2L1 antibody - ab83911 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MSL2L1 antibody (ab83911) at 1 µg/ml (in 5% skim milk/ PBS buffer) + HeLa cell lysate at 10 µg with gel concentration: 12%SecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-MSL2L1 antibody - N-terminal - ab173089 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MSL2L1 antibody - N-terminal (ab173089) at 1/100 dilution + CEM cell line lysate at 35 µg

Anti-MSL2 Antibody (aa4-32, APC) - LS-C263598 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (aa4-32, AP) - LS-C263597 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (aa4-32, PE) - LS-C263602 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (aa4-32, FITC) - LS-C263601 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (aa4-32, Biotin) - LS-C263599 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (aa3-32) - LS-C323133 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (aa4-32, Azide-free, HRP) - LS-C263600 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MSL2 Antibody (N-Terminus) - LS-C102012 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
MSL2 / MSL2L1 antibody LS-C102012 Western blot of HeLa lysate.

Anti-MSL2 Antibody (aa4-32) - LS-C158319 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
MSL2 Antibody western blot of CEM cell line lysates (35 ug/lane). The MSL2 antibody detected the MSL2 protein (arrow).

MSL2L1 Antibody - NBP1-83853 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal

MSL2L1 Antibody - NBP1-52987 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

MSL2L1 Antibody - H00055167-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MSL2L1 Antibody [H00055167-D01P] - Analysis of MSL2 expression in transfected 293T cell line by MSL2 polyclonal antibody.Lane 1: MSL2L1 transfected lysate(62.50 KDa).Lane 2: Non-transfected lysate.

MSL2L1 Antibody - H00055167-B02P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

MSL2L1 Antibody - H00055167-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: MSL2L1 Antibody [H00055167-B01] - analysis of MSL2L1 expression in transfected 293T cell line by MSL2L1 MaxPab polyclonal antibody (B01). Lane 1: MSL2L1 transfected lysate (62.50 KDa). Lane 2: Non-transfected lysate.

MSL2L1 Antibody - H00055167-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

MSL2L1 Antibody (4C5) - H00055167-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C5
Sandwich ELISA: MSL2L1 Antibody (4C5) [H00055167-M02] - Detection limit for recombinant GST tagged MSL2 is 0.1 ng/ml as a capture antibody.

MSL2L1 Antibody (3A4) - H00055167-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3A4
Sandwich ELISA: MSL2L1 Antibody (3A4) [H00055167-M01] - Detection limit for recombinant GST tagged MSL2 is 0.1 ng/ml as a capture antibody.

Anti-MSL2 antibody produced in rabbit - HPA003413 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-MSL2L1: <B>Cat. No. HPA003413</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human pancreas shows cytoplasmic positivity in exocrine glandular cells and islet cells.

Monoclonal Anti-MSL2 antibody produced in mouse - SAB1405144 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4C5

Anti-MSL2 antibody produced in mouse - SAB1407627 from Sigma-Aldrich

Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-MSL2: <B>Cat. No. SAB1407627</B>: Antibody concentration: 10 μg/mL using HeLa cell.
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