MSL2

Gene Symbol MSL2
Entrez Gene 55167
Alt Symbol MSL-2, MSL2L1, RNF184
Species Human
Gene Type protein-coding
Description male-specific lethal 2 homolog (Drosophila)
Other Description E3 ubiquitin-protein ligase MSL2|MSL2-like 1|male-specific lethal 2-like 1|male-specific lethal-2 homolog 1|ring finger protein 184
Swissprots Q9NVS4 G5E9I1 Q8NDB4 Q9HCI7 Q0D2P1 B4DYL4
Accessions EAW79119 EAW79120 Q9HCI7 AB046805 BAB13411 AK001408 BAA91673 AK091956 AK292557 BAF85246 AK302491 BAG63776 AL834289 CAD38963 AW237818 AW271295 BC032719 AAH32719 BC093764 AAH93764 BC093790 AAH93790 DA674784 DC409643 XM_005247571 XP_005247628 XM_005247572 XP_005247629 XM_006713684 XP_006713747 XM_011512949 XP_011511251 NM_001145417 NP_001138889 NM_018133 NP_060603
Function Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. {ECO:0000269|PubMed:21726816}.

RNF184 CRISPR/Cas9 KO Plasmid (h) - sc-408901 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 HDR Plasmid (h) - sc-408901-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 Double Nickase Plasmid (h) - sc-408901-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 Double Nickase Plasmid (h2) - sc-408901-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 CRISPR Activation Plasmid (h) - sc-408901-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 CRISPR Activation Plasmid (h2) - sc-408901-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 Lentiviral Activation Particles (h) - sc-408901-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 Lentiviral Activation Particles (h2) - sc-408901-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

RNF184 siRNA (h) - sc-78467 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RNF184 shRNA Plasmid (h) - sc-78467-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

RNF184 shRNA (h) Lentiviral Particles - sc-78467-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU039501 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN14650 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND14650 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR11253 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr11253

MSL2 siRNA (Human) - CRJ0521 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

MSL2L1 RNAi - H00055167-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human MSL2 (NM_018133.3) - SHH345708 from Creative biogene

Category siRNA
Species Reactivities Human

MSL2 shRNA Plasmid (Human) - CHJ0521 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

MSL2 miRNA 3'UTR clone - MiUTR4H-TG05687 from Creative biogene

Species Reactivities Human
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