Gene Symbol | MSL2 |
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Entrez Gene | 55167 |
Alt Symbol | MSL-2, MSL2L1, RNF184 |
Species | Human |
Gene Type | protein-coding |
Description | male-specific lethal 2 homolog (Drosophila) |
Other Description | E3 ubiquitin-protein ligase MSL2|MSL2-like 1|male-specific lethal 2-like 1|male-specific lethal-2 homolog 1|ring finger protein 184 |
Swissprots | Q9NVS4 G5E9I1 Q8NDB4 Q9HCI7 Q0D2P1 B4DYL4 |
Accessions | EAW79119 EAW79120 Q9HCI7 AB046805 BAB13411 AK001408 BAA91673 AK091956 AK292557 BAF85246 AK302491 BAG63776 AL834289 CAD38963 AW237818 AW271295 BC032719 AAH32719 BC093764 AAH93764 BC093790 AAH93790 DA674784 DC409643 XM_005247571 XP_005247628 XM_005247572 XP_005247629 XM_006713684 XP_006713747 XM_011512949 XP_011511251 NM_001145417 NP_001138889 NM_018133 NP_060603 |
Function | Component of histone acetyltransferase complex responsible for the majority of histone H4 acetylation at lysine 16 which is implicated in the formation of higher-order chromatin structure. Acts as an E3 ubiquitin ligase that promotes monoubiquitination of histone H2B at 'Lys-35' (H2BK34Ub), but not that of H2A. This activity is greatly enhanced by heterodimerization with MSL1. H2B ubiquitination in turn stimulates histine H3 methylation at 'Lys-4' (H3K4me) and 'Lys-79' (H3K79me) and leads to gene activation, including that of HOXA9 and MEIS1. {ECO:0000269|PubMed:21726816}. |
Human MSL2L1 full length protein - ab162995 from Abcam
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Human MSL2L1 protein fragment - ab162996 from Abcam
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MSL2 Antibody Blocking Peptide - LS-E4961 from LifeSpan Bioscience
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MSL2 Antibody Blocking Peptide - LS-E15914 from LifeSpan Bioscience
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Recombinant Human MSL2L1 Protein - H00055167-P01 from Novus Biologicals
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Recombinant Human MSL2L1 Protein - H00055167-Q01 from Novus Biologicals
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MSL2-Antibody-N-term-Blocking-Peptide - BP17353a from Abgent, a WuXi AppTec company
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MSL2L1 Blocking Peptide - 33R-6835 from Fitzgerald
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MSL2 - H00055167-P01-10 from Acris Antibodies
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MSL2 - H00055167-P01-25 from Acris Antibodies
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MSL2 - H00055167-Q01-10 from Acris Antibodies
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MSL2 - H00055167-Q01-25 from Acris Antibodies
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MSL2 fusion protein - ag18727 from Proteintech Group
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MSL2 fusion protein - ag18878 from Proteintech Group
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Recombinant Human MSL2, His-tagged - MSL2-83H from Creative Biomart
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Recombinant Human Male-specific lethal 2 homolog(MSL2) - CSB-YP875722HU CSB-EP875722HU CSB-BP875722HU CSB-MP875722HU from Cusabio
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MSL2 (full length, N-term HIS tag, transcript variant 1) - TP760587 from Acris Antibodies
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MSL2L1 Recombinant Protein Antigen - NBP1-83853PEP from Novus Biologicals
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MSL2 Peptide, Human - M34GP09827H from Creative Peptides
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MSL2L1 Recombinant Protein Antigen - NBP2-55556PEP from Novus Biologicals
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Male-specific lethal 2 homolog (MSL2), Recombinant Protein - MBS1422521 from MyBioSource
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