CUEDC2

Gene Symbol CUEDC2
Entrez Gene 79004
Alt Symbol C10orf66, bA18I14.5
Species Human
Gene Type protein-coding
Description CUE domain containing 2
Other Description CUE domain-containing protein 2
Swissprots D3DR88 Q9H467 Q9BWG8
Accessions CAI93450 EAW49696 EAW49697 EAW49698 Q9H467 AB025425 BAB87809 AB232358 BAE19942 AF086406 BC000262 AAH00262 BF002772 BM756951 CX165866 NM_024040 NP_076945
Function Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. {ECO:0000269|PubMed:17347654, ECO:0000269|PubMed:21572428}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17347654}. Nucleus {ECO:0000269|PubMed:17347654}.
Tissue Specificity Significantly up-regulated in breast tumor tissues compared with matched adjacent normal tissues (at protein level). Levels inversely correlate with ESR1 in breast cancers and are lower in low-grade tumors compared to high-grade tumors.

CUEDC2 Antibody - 12294 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using CUEDC2 Antibody.

CUEDC2 (N-15) - sc-242520 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CUEDC2 (N-15): sc-242520. Western blot analysis of CUEDC2 expression in mouse brain tissue extract.

Anti-CUEDC2 antibody - ab79036 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CUEDC2 antibody (ab79036) at 1 µg/mlLane 2 : Anti-CUEDC2 antibody (ab79036) at 2 µg/mlLane 1 : HeLa cell lysateLane 2 : HeLa cell lysateLysates/proteins at 15 µg per lane.

Anti-CUEDC2 antibody - ab109649 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-CUEDC2 antibody (ab109649) at 1 µg/mlLane 2 : Anti-CUEDC2 antibody (ab109649) at 2 µg/mlLane 1 : HeLa cell lysateLane 2 : HeLa cell lysate

Anti-CUEDC2 antibody - ab177567 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-CUEDC2 antibody (ab177567) at 1 µg/ml + Mouse heart lysate at 10 µg

Anti-CUEDC2 antibody [2H6] - ab156945 from Abcam

Prices $370.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 2H6
All lanes : Anti-CUEDC2 antibody [2H6] (ab156945) at 1/2000 dilutionLane 1 : HEK293T cell lysate transfected with pCMV6-ENTRY controlLane 2 : HEK293T cell lysate transfected with pCMV6-ENTRY CUEDC2 cDNALysates/proteins at 5 µg per lane.

Anti-CUEDC2 antibody - C-terminal - ab135613 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CUEDC2 antibody - C-terminal (ab135613) at 1/50 dilution + Y79 cell line lysates at 35 µg

Anti-CUEDC2 antibody - N-terminal - ab176863 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human fetal spleen tissue labeling CUEDC2 with ab176863 at a 1/100 dilution.

Anti-CUEDC2 Antibody (aa239-267) IHC-plus™ - LS-B10704 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CUEDC2 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B10704 dilution 1:75.

Anti-CUEDC2 Antibody (clone 2H6) - LS-C337044 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2H6
Western blot of extracts (35ug) from 9 different cell lines by using anti-CUEDC2 monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).

Anti-CUEDC2 Antibody (aa267-287) - LS-C313497 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CUEDC2 antibody. IHC(P): Human Thyroid Cancer Tissue.

Anti-CUEDC2 Antibody (C-Terminus) IHC-plus™ - LS-B3840 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Anti-CUEDC2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3840 concentration 5 ug/ml.

Anti-CUEDC2 Antibody (aa250-300) - LS-C148465 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of CUEDC2 in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide, 3) NIH 3T3 cell lysate, and 4) human spleen cell lysate using LS-C148465 at 0.5 ug/ml.

Anti-CUEDC2 Antibody (aa50-100) - LS-C148498 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
IHC ofCUEDC2 in formalin-fixed paraffin-embedded human thyroid tissue using an isotype control (top left) and LS-C148498 (bottom left, right) at5 ug/ml.

Anti-CUEDC2 Antibody (aa71-120) - LS-C186723 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of Mouse Heart. Cuedc2 antibody dilution 1.0 ug/ml.

Anti-CUEDC2 Antibody (aa262-266) - LS-C205240 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of extracts from HepG2, HeLa and 293 cells using CUEDC2 antibody.

CUEDC2 Antibody - NBP2-24639 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CUEDC2 Antibody [NBP2-24639] - analysis of CUEDC2 in MCF7 cell lysate in the 1) absence and 2) presence of immunizing peptide, 3) NIH 3T3 cell lysate, and 4) human spleen cell lysate using this antibody. 5 ug/ml.

CUEDC2 Antibody - NBP1-88538 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: CUEDC2 Antibody [NBP1-88538] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli & cytoplasm.

CUEDC2 Antibody - NBP2-24684 from Novus Biologicals

Prices $99.00, $229.00
Sizes 25 µg, 100 µg
Host Rabbit
Clonality Polyclonal

CUEDC2 Antibody - NBP1-77334 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: CUEDC2 Antibody [NBP1-77334] - HeLa cell lysate with CUEDC2 antibody at (A) 1 and (B) 2 ug/ml.

CUEDC2 Antibody - NBP1-52203 from Novus Biologicals

Prices $399.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: CUEDC2 Antibody [NBP1-52203] - Staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.

CUEDC2 Polyclonal Antibody - bs-4608R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded mouse brain labeled with Anti-CUEDC2/CUE domain containing 2 Polyclonal Antibody, Unconjugated (bs-4608R) at 1:4000 followed by conjugation to the secondary antibody and DAB staining

Anti-CUEDC2 antibody produced in rabbit - SAB2900777 from Sigma-Aldrich

Prices $465.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CUEDC2 (Internal), antibody produced in rabbit: <B>Cat. No. SAB2900777</B>: Anti-CUEDC2 antibody IHC staining of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 μg/mL.

Anti-CUEDC2 antibody produced in rabbit - HPA036544 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CUEDC2: <B>Cat. No. HPA036544</B>: Immunohistochemical staining of human bone marrow shows distinct positivity megakaryocytes and thrombocytes.

Anti-CUEDC2 antibody produced in rabbit - PRS4839 from Sigma-Aldrich

Prices $347.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CUEDC2: <B>Cat. No. PRS4839</B> Western blot analysis of CUEDC2 in HeLa cell lysate with CUEDC2 antibody at (A) 1 and (B) 2 μg/mL.
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