CUEDC2

Gene Symbol CUEDC2
Entrez Gene 79004
Alt Symbol C10orf66, bA18I14.5
Species Human
Gene Type protein-coding
Description CUE domain containing 2
Other Description CUE domain-containing protein 2
Swissprots D3DR88 Q9H467 Q9BWG8
Accessions CAI93450 EAW49696 EAW49697 EAW49698 Q9H467 AB025425 BAB87809 AB232358 BAE19942 AF086406 BC000262 AAH00262 BF002772 BM756951 CX165866 NM_024040 NP_076945
Function Down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. Also involved in 17 beta-estradiol-induced ESR1 degradation. Controls PGR protein levels through a similar mechanism. {ECO:0000269|PubMed:17347654, ECO:0000269|PubMed:21572428}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:17347654}. Nucleus {ECO:0000269|PubMed:17347654}.
Tissue Specificity Significantly up-regulated in breast tumor tissues compared with matched adjacent normal tissues (at protein level). Levels inversely correlate with ESR1 in breast cancers and are lower in low-grade tumors compared to high-grade tumors.

CUEDC2 CRISPR/Cas9 KO Plasmid (h) - sc-410505 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 HDR Plasmid (h) - sc-410505-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 Double Nickase Plasmid (h) - sc-410505-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 Double Nickase Plasmid (h2) - sc-410505-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 CRISPR Activation Plasmid (h) - sc-410505-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 CRISPR Activation Plasmid (h2) - sc-410505-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 Lentiviral Activation Particles (h) - sc-410505-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 Lentiviral Activation Particles (h2) - sc-410505-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CUEDC2 siRNA (h) - sc-90791 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CUEDC2 shRNA Plasmid (h) - sc-90791-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CUEDC2 shRNA (h) Lentiviral Particles - sc-90791-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU055071 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN6771 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND6771 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR00578 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr00578

CUEDC2 siRNA (Human) - CRJ2248 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CUEDC2 - MBS8233408 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CUEDC2 (NM_024040.2) - SHH271817 from Creative biogene

Category siRNA
Species Reactivities Human

CUEDC2 shRNA Plasmid (Human) - CHJ2248 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CUEDC2 miRNA 3'UTR clone - MiUTR1H-02552 from Creative biogene

Species Reactivities Human
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