PDE4B

Gene Symbol	PDE4B
Entrez Gene	5142
Alt Symbol	DPDE4, PDEIVB
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 4B, cAMP-specific
Other Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B|dunce-like phosphodiesterase E4|phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
Swissprots	Q5TEK5 O15443 Q5TEK4 Q13945 A5YW33 Q5TEK6 Q07343
Accessions	CAV28613 EAX06524 EAX06525 Q07343 AA206316 AA453531 AB209081 BAD92318 AK000989 AK127365 AK289969 BAF82658 AK290006 BAF82695 AK290206 BAF82895 AK294441 BAG57682 AW519027 BC036108 BC046161 BC071607 BC101480 AAI01481 BC105040 AAI05041 BF513098 CN268011 CR749667 CAH18458 DA103627 DA126733 DA311741 DA332822 DC399916 EF595686 ABQ85407 KJ534916 AHW56556 KJ534917 AHW56557 KJ535082 AHW56721 L12685 AAA35642 L12686 AAA35643 L20966 AAA03589 M97515 AAA36426 U85048 AAB96381 XM_005270923 XP_005270980 XM_005270924 XP_005270981 XM_005270925 XP_005270982 XM_006710680 XP_006710743 XM_011541565 XP_011539867 XM_011541566 XP_011539868 NM_001037339 NP_001032416 NM_001037340 NP_001032417 NM_001037341 NP_001032418 NM_001297440 NP_001284369 NM_001297441 NP_001284370 NM_001297442 NP_001284371 NM_002600 NP_002591
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. {ECO:0000269|PubMed:10846163, ECO:0000269|PubMed:15003452}.
Tissue Specificity	Expressed in brain, heart, lung and skeletal muscle.
Top Pathways	Morphine addiction, cAMP signaling pathway, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

cAMP-specific 3',5'-cyclic phosphodiesterase 4B, PDE4B, Human, ELISA Kit - E0433h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.156-10 ng/mL

ELISA Kit for Phosphodiesterase 4B, cAMP Specific (PDE4B) - SEF642Ra from Uscn Life Science Inc. Category ELISA Kit Sensitivity The minimum detectable dose of this kit is typically less than 0.065ng/mL. Range 0.156-10ng/mL The standard curve concentrations used for the ELISA’s were 10ng/mL, 5ng/mL, 2.5ng/mL, 1.25ng/mL, 0.625ng/mL, 0.313ng/mL, 0.156ng/mL

Human PDE4B ELISA Kit (Custom ELISA) - LS-F14548 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity To be determined Range 78-5000 pg/ml

Human cAMP-specific 3',5'-cyclic phosphodiesterase 4B ELISA Kit - abx253859 from Abbexa Category ELISA Kit Range 0.156 ng/ml - 10 ng/ml

Rat PDE4B ELISA Kit (Sandwich ELISA) - LS-F13377 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 78 Range 78-5000 pg/ml

Rat PDE4B ELISA Kit (Sandwich ELISA) - LS-F25498 from LifeSpan Bioscience Category ELISA Kit Prices $840.00 Sizes 1 plate Sensitivity 0.065 ng/ml Range 78-5000 pg/ml

Human cAMP-specific 3',5'-cyclic phosphodiesterase 4B ELISA Kit - EKE53600 from Biomatik Category ELISA Kit Prices $685.40, $2,912.95, $5,483.20 Sizes 96 t, 5x96t, 10x96t Sensitivity The minimum detectable dose of this kit is typically less than 0.078 ng/mL Range 0.156-10 ng/mL

PDE4B - EKH1806 from Nordic BioSite Sensitivity 0.094ng/ml Range 0.156-10ng/ml

Human PDE4B ELISA Kit - E006310 from Biobool Category ELISA Kit Sensitivity < 0.094ng/ml

PDE4B ELISA Kit (Human) (OKEH04320) - OKEH04320 from Aviva Systems Biology Category ELISA Kit Prices $596.00 Sizes 96 wells Sensitivity < 0.07 ng/mL Range 0.15 - 10 ng/mL

anti-PDE4B antibody - ARG10801 from Arigo Biolaboratories Category ELISA Kit

cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ELISA Kit - MBS760982 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.094ng/ml Range 0.156-10ng/ml

cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ELISA Kit - MBS2885558 from MyBioSource Category ELISA Kit Prices $380.00, $500.00, $2,170.00, $3,840.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Range 0.156-10 ng/mL

cAMP-specific 3',5'-cyclic phosphodiesterase 4B, ELISA Kit - MBS761396 from MyBioSource Category ELISA Kit Prices $295.00, $390.00, $1,615.00, $3,015.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 46.9pg/ml Range 78-5000pg/ml

Human PDE4B ELISA Kit (Sandwich ELISA) - LS-F32760 from LifeSpan Bioscience Category ELISA Kit Sensitivity 0.094 Range 78-5000 pg/ml

Rat PDE4B ELISA Kit (Sandwich ELISA) - LS-F32761 from LifeSpan Bioscience Category ELISA Kit Sensitivity 46.9 Range 78-5000 pg/ml

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