PDE4B

Gene Symbol	PDE4B
Entrez Gene	5142
Alt Symbol	DPDE4, PDEIVB
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 4B, cAMP-specific
Other Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B|dunce-like phosphodiesterase E4|phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
Swissprots	Q5TEK5 O15443 Q5TEK4 Q13945 A5YW33 Q5TEK6 Q07343
Accessions	CAV28613 EAX06524 EAX06525 Q07343 AA206316 AA453531 AB209081 BAD92318 AK000989 AK127365 AK289969 BAF82658 AK290006 BAF82695 AK290206 BAF82895 AK294441 BAG57682 AW519027 BC036108 BC046161 BC071607 BC101480 AAI01481 BC105040 AAI05041 BF513098 CN268011 CR749667 CAH18458 DA103627 DA126733 DA311741 DA332822 DC399916 EF595686 ABQ85407 KJ534916 AHW56556 KJ534917 AHW56557 KJ535082 AHW56721 L12685 AAA35642 L12686 AAA35643 L20966 AAA03589 M97515 AAA36426 U85048 AAB96381 XM_005270923 XP_005270980 XM_005270924 XP_005270981 XM_005270925 XP_005270982 XM_006710680 XP_006710743 XM_011541565 XP_011539867 XM_011541566 XP_011539868 NM_001037339 NP_001032416 NM_001037340 NP_001032417 NM_001037341 NP_001032418 NM_001297440 NP_001284369 NM_001297441 NP_001284370 NM_001297442 NP_001284371 NM_002600 NP_002591
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. {ECO:0000269|PubMed:10846163, ECO:0000269|PubMed:15003452}.
Tissue Specificity	Expressed in brain, heart, lung and skeletal muscle.
Top Pathways	Morphine addiction, cAMP signaling pathway, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active dog PDE4B full length protein - ab198425 from Abcam Category Protein Prices $1,250.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Dog

Active dog PDE4B full length protein - ab198483 from Abcam Category Protein Prices $1,250.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Dog

Active human PDE4B full length protein - ab56612 from Abcam Category Protein Prices $466.00 Sizes 10 µg Source Baculovirus infected sf9 cells Species Human

Active human PDE4B protein fragment - ab125582 from Abcam Category Protein Prices $302.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Active rat PDE4B full length protein - ab198434 from Abcam Category Protein Prices $1,250.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Rat

Human PDE4B protein fragment - ab159072 from Abcam Category Protein Source Wheat germ Species Human

PDE4B peptide - ab169989 from Abcam Category Peptide

PDE4B peptide - ab170991 from Abcam Category Peptide

PDE4B Antibody Blocking Peptide - LS-E1151 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE4B Antibody Blocking Peptide - LS-E20391 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE4B Antibody Blocking Peptide - LS-E20392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE4B Antibody Blocking Peptide - LS-E25194 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PDE4B Antibody Blocking Peptide - LS-E26039 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human PDE4B Protein - H00005142-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

PDE4B-Antibody-Center-Blocking-peptide - BP11684c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PDE4B blocking peptide - GTX89403-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human, Mouse, Rat

Human PDE4B His GST tag protein - orb84149 from Biorbyt Category Protein Prices $323.00, $612.00 Sizes 20 μg, 50 μg Source Insect Species Human

Pde4b Blocking Peptide - 33R-5530 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDE4B Blocking Peptide - 33R-7502 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

PDE4B/C/D Blocking Peptide - abx063057 from Abbexa Category Peptide Species Human

PDE4B Peptide - AC21-0015-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PDE4B Peptide - AC21-0867-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

PDE4B - H00005142-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

PDE4B - H00005142-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PDE4B control peptide - AP10221CP-N from Acris Antibodies Category Peptide Prices $255.00 Sizes 100 µg

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