PDE4B

Gene Symbol	PDE4B
Entrez Gene	5142
Alt Symbol	DPDE4, PDEIVB
Species	Human
Gene Type	protein-coding
Description	phosphodiesterase 4B, cAMP-specific
Other Description	cAMP-specific 3',5'-cyclic phosphodiesterase 4B|dunce-like phosphodiesterase E4|phosphodiesterase 4B, cAMP-specific (phosphodiesterase E4 dunce homolog, Drosophila)
Swissprots	Q5TEK5 O15443 Q5TEK4 Q13945 A5YW33 Q5TEK6 Q07343
Accessions	CAV28613 EAX06524 EAX06525 Q07343 AA206316 AA453531 AB209081 BAD92318 AK000989 AK127365 AK289969 BAF82658 AK290006 BAF82695 AK290206 BAF82895 AK294441 BAG57682 AW519027 BC036108 BC046161 BC071607 BC101480 AAI01481 BC105040 AAI05041 BF513098 CN268011 CR749667 CAH18458 DA103627 DA126733 DA311741 DA332822 DC399916 EF595686 ABQ85407 KJ534916 AHW56556 KJ534917 AHW56557 KJ535082 AHW56721 L12685 AAA35642 L12686 AAA35643 L20966 AAA03589 M97515 AAA36426 U85048 AAB96381 XM_005270923 XP_005270980 XM_005270924 XP_005270981 XM_005270925 XP_005270982 XM_006710680 XP_006710743 XM_011541565 XP_011539867 XM_011541566 XP_011539868 NM_001037339 NP_001032416 NM_001037340 NP_001032417 NM_001037341 NP_001032418 NM_001297440 NP_001284369 NM_001297441 NP_001284370 NM_001297442 NP_001284371 NM_002600 NP_002591
Function	Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. May be involved in mediating central nervous system effects of therapeutic agents ranging from antidepressants to antiasthmatic and anti-inflammatory agents. {ECO:0000269|PubMed:10846163, ECO:0000269|PubMed:15003452}.
Tissue Specificity	Expressed in brain, heart, lung and skeletal muscle.
Top Pathways	Morphine addiction, cAMP signaling pathway, Purine metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PDE4B overexpression lysate - LY400417 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

PDE4B 293 Cell Lysate - 400439 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg Species Drosophila

PDE4B 293 Cell Lysate - 400866 from ABBIOTEC Category Cell Lysate Prices $672.00 Sizes 100 µg Species Drosophila

PDE4B Overexpression Lysate (Native) - NBL1-14219 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

PDE4B Overexpression Lysate (Native) - NBP2-08546 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

PDE4B Overexpression Lysate (Native) - NBL1-14220 from Novus Biologicals Category Cell Lysate Prices $529.00 Sizes 100 µg

PDE4B Over-expression Lysate Product - GWB-622C15 from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

PDE4B Over-expression Lysate Product - GWB-5B804D from Genway Biotech Category Cell Lysate Prices $756.00 Sizes 100 µg Species Human

Human PDE4B / DPDE4 Insect Cell Lysate (WB positive control) - 11527-H20BL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human PDE4B Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175009 from Biorbyt Category Cell Lysate Prices $604.00 Sizes 300 μg Species Human

Panoply™ Human PDE4B Knockdown Stable Cell Line - CSC-DC011504 from Creative biogene Category Cell Line Species Human

Search more