Gene Symbol | HECW2 |
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Entrez Gene | 57520 |
Alt Symbol | NEDL2 |
Species | Human |
Gene Type | protein-coding |
Description | HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2 |
Other Description | E3 ubiquitin-protein ligase HECW2|HECT, C2 and WW domain-containing protein 2|NEDD4-like E3 ubiquitin-protein ligase 2|NEDD4-related E3 ubiquitin ligase NEDL2 |
Swissprots | Q9NPS9 Q68DF8 Q17RT5 B8ZZB4 Q9P2P5 |
Accessions | EAW70123 Q9P2P5 AB037722 BAA92539 AL390186 CAB99103 BC117194 AAI17195 BC117198 AAI17199 CR749424 CAH18262 XM_006712646 XP_006712709 XM_006712648 XP_006712711 NM_001304840 NP_001291769 NM_020760 NP_065811 |
Function | E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. {ECO:0000269|PubMed:12890487}. |
Subcellular Location | Cytoplasm {ECO:0000250}. |
Tissue Specificity | Predominantly expressed in adult brain, lung and heart. {ECO:0000269|PubMed:12890487}. |
Human NEDL2 peptide - ab23243 from Abcam
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Human NEDL2 protein fragment - ab163576 from Abcam
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NEDL2 / HECW2 Antibody Blocking Peptide - LS-E4397 from LifeSpan Bioscience
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NEDL2 / HECW2 Antibody Blocking Peptide - LS-E25764 from LifeSpan Bioscience
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Recombinant Human NEDL2 Protein - H00057520-Q01 from Novus Biologicals
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HECW2-Antibody-Center-Blocking-Peptide - BP16705c from Abgent, a WuXi AppTec company
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NEDL2 blocking peptide - GTX13821-PEP from GeneTex
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HECW2 Peptide - orb224311 from Biorbyt
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NEDL2 Peptide - AC21-0593-P from Abcore
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NEDL2 - H00057520-Q01-10 from Acris Antibodies
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NEDL2 - H00057520-Q01-25 from Acris Antibodies
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NEDL2 Peptide - 45-941P from ProSci
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HECW2 Blocking Peptide - CBP3425 from Cohesion Biosciences
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Recombinant Human E3 ubiquitin-protein ligase HECW2(HECW2) ,partial - CSB-YP889188HU CSB-EP889188HU CSB-BP889188HU CSB-MP889188HU from Cusabio
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NEDL2 - TP316544 from Acris Antibodies
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EndoNEDD4/NEDL2, Peptide - MBS426144 from MyBioSource
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NEDL2 Recombinant Protein Antigen - NBP1-92174PEP from Novus Biologicals
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HECW2 Blocking Peptide - abx162287 from Abbexa
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HECW2 Peptide, Human - M34GP06925H from Creative Peptides
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E3 ubiquitin-protein ligase HECW2 (HECW2), partial, Recombinant Protein - MBS1353383 from MyBioSource
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