CSF1

Gene Symbol	CSF1
Entrez Gene	1435
Alt Symbol	CSF-1, MCSF
Species	Human
Gene Type	protein-coding
Description	colony stimulating factor 1 (macrophage)
Other Description	lanimostim|macrophage colony-stimulating factor 1
Swissprots	Q9UQR8 Q5VVF3 Q14806 Q14086 A8K6J5 Q13130 Q5VVF4 P09603
Accessions	AAB59527 CAA29479 CAJ32234 CAJ32235 CAJ32236 CBX54357 CBX55878 CBX55879 CBX55880 CCA65433 CCA65434 CCA65435 EAW56416 EAW56417 EAW56418 EAW56419 EAW56420 EAW56421 P09603 AB208952 BAD92189 AI758702 AK291660 BAF84349 AK300401 BAG62132 AK311440 BC021117 AAH21117 DA414355 DB287787 JF803735 AEF12310 M27087 AAA59573 M37435 AAA52117 M64592 AAA59572 M76453 AAA52120 U22386 AAA64849 X05825 CAA29265 NM_000757 NP_000748 NM_172210 NP_757349 NM_172211 NP_757350 NM_172212 NP_757351
Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. {ECO:0000269|PubMed:16337366, ECO:0000269|PubMed:19934330, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:1531650, ECO:0000269|PubMed:3264877}; Single-pass type I membrane protein {ECO:0000269|PubMed:1531650, ECO:0000269|PubMed:3264877}.
Top Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Osteoclast differentiation, Rheumatoid arthritis, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

M-CSF Human ELISA Kit - ab100590 from Abcam Category ELISA Kit Prices $489.00 Sizes 1 x 96 tests Sensitivity < 5 pg/ml Range 2.78 pg/ml - 2000 pg/ml

Human CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F5148 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 2.9 pg/ml Range 2.743-666.7 pg/ml

Mouse CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F5149 from LifeSpan Bioscience Category ELISA Kit Prices $470.00 Sizes 1 plate Sensitivity 2.37 pg/ml Range 2.743-666.7 pg/ml

Rat CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F5528 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 3.3 pg/ml Range 2.743-666.7 pg/ml

Human CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F2499 from LifeSpan Bioscience Category ELISA Kit Prices $480.00 Sizes 1 plate Sensitivity 10 pg/ml Range 2.743-666.7 pg/ml

Human CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F149 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 2.743 pg/ml Range 2.743-666.7 pg/ml

Mouse CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F273 from LifeSpan Bioscience Category ELISA Kit Prices $460.00, $840.00, $1,960.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity 1.434 pg/ml Range 2.743-666.7 pg/ml

Human CSF1 / MCSF ELISA Kit (Custom ELISA) - LS-F460 from LifeSpan Bioscience Category ELISA Kit Prices $670.00, $1,190.00, $2,570.00 Sizes 1 plate, 2 plate, 5 plate Sensitivity To be determined Range 2.743-666.7 pg/ml

Human CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F648 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 2.743-666.7 pg/ml

Mouse CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F620 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 2.743-666.7 pg/ml

Rat CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F11223 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 15.6 Range 2.743-666.7 pg/ml

Human CSF1 / MCSF ELISA Kit (Sandwich ELISA) - LS-F11222 from LifeSpan Bioscience Category ELISA Kit Prices $530.00 Sizes 1 plate Sensitivity 31.2 Range 2.743-666.7 pg/ml

Human Cardiotrophin-1 ELISA Kit - RAB0107 from Sigma-Aldrich Category ELISA Kit Prices $438.50 Sizes 1 kt

Human M-CSF / CSF1 ELISA Kit - RAB0098 from Sigma-Aldrich Category ELISA Kit Prices $423.50 Sizes 1 kt

Human M-CSF Quantikine ELISA Kit - DMC00B from R&D Systems Category ELISA Kit Prices $509.00, $2,440.00, $16,540.00 Sizes 1 kit, 1 pack (6 Plates), 1 pack (50 Plates)

Human M-CSF Quantikine PharmPak (50 Plates) - PDMC00B from R&D Systems Category ELISA Kit Sensitivity 47.3 pg/mL Range 78.1 - 5,000 pg/mL (Serum, Heparin Plasma, Saliva, Cell Culture Supernates, EDTA Plasma, Urine)

Human M-CSF Quantikine SixPak (6 Plates) - SMC00B from R&D Systems Category ELISA Kit Sensitivity 47.3 pg/mL Range 78.1 - 5,000 pg/mL (Serum, Heparin Plasma, Saliva, Cell Culture Supernates, EDTA Plasma, Urine)

Mouse M-CSF Quantikine ELISA Kit - MMC00 from R&D Systems Category ELISA Kit Prices $479.00 Sizes 1 kit Sensitivity 5 pg/mL Range 31.2 - 2,000 pg/mL (Cell Culture Supernates, Serum, EDTA Plasma)

Mouse M-CSF DuoSet ELISA - DY416 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Human M-CSF DuoSet ELISA - DY216 from R&D Systems Category ELISA Kit Prices $649.00 Sizes 1 kit (for 15 Plates) Range 15.60 - 1,000 pg/mL

Human MCSF ELISA Kit - 55R-1640 from Fitzgerald Category ELISA Kit Prices $350.00 Sizes 1 kit

Human MCSF ELISA kit - 55R-1993 from Fitzgerald Category ELISA Kit Prices $435.00 Sizes 96 tests

Mouse MCSF ELISA Kit - 55R-1641 from Fitzgerald Category ELISA Kit Prices $430.00 Sizes 1 kit

M-CSF ELISA Kit (Human) : 96 Wells (OKAG00151) - OKAG00151 from Aviva Systems Biology Category ELISA Kit Prices $390.00 Sizes 96 wells Sensitivity 16 pg/mL Range 16-1,000 pg/mL

Human MCSF ELISA Kit - abx152293 from Abbexa Category ELISA Kit Sensitivity 0.97 pg/ml Range 31.25 pg/ml - 2000 pg/ml

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