CSF1

Gene Symbol	CSF1
Entrez Gene	1435
Alt Symbol	CSF-1, MCSF
Species	Human
Gene Type	protein-coding
Description	colony stimulating factor 1 (macrophage)
Other Description	lanimostim|macrophage colony-stimulating factor 1
Swissprots	Q9UQR8 Q5VVF3 Q14806 Q14086 A8K6J5 Q13130 Q5VVF4 P09603
Accessions	AAB59527 CAA29479 CAJ32234 CAJ32235 CAJ32236 CBX54357 CBX55878 CBX55879 CBX55880 CCA65433 CCA65434 CCA65435 EAW56416 EAW56417 EAW56418 EAW56419 EAW56420 EAW56421 P09603 AB208952 BAD92189 AI758702 AK291660 BAF84349 AK300401 BAG62132 AK311440 BC021117 AAH21117 DA414355 DB287787 JF803735 AEF12310 M27087 AAA59573 M37435 AAA52117 M64592 AAA59572 M76453 AAA52120 U22386 AAA64849 X05825 CAA29265 NM_000757 NP_000748 NM_172210 NP_757349 NM_172211 NP_757350 NM_172212 NP_757351
Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. {ECO:0000269|PubMed:16337366, ECO:0000269|PubMed:19934330, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:1531650, ECO:0000269|PubMed:3264877}; Single-pass type I membrane protein {ECO:0000269|PubMed:1531650, ECO:0000269|PubMed:3264877}.
Top Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Osteoclast differentiation, Rheumatoid arthritis, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-CSF1-cDNA-Clone - DC10265 from Abgent, a WuXi AppTec company Prices $747.90 Sizes 10 µg Species Human Accession BC021117

CSF1 - MBS1267651 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC021117

Human CSF1 ORF clone(NM_172212.2) - CDCL183735 from Creative Biomart Species Human Accession NM_172212.2

Human CSF1 ORF Clone(NM_000757.5) - CDCL159877 from Creative Biomart Species Human Accession NM_000757.5

Human CSF1 transcript variant 4 Gene cDNA clone plasmid - HG11792-G from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11792-ACG from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11792-NF from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11792-NY from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11792-CF from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11792-NM from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11792-CM from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, N-His tag - HG11792-NH from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid - HG11792-G-N from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG11792-ACR from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, C-His tag - HG11792-CH from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid - HG11792-UT from Sino Biological Species Human

Human M-CSF/CSF-1 transcript variant 4 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11792-CY from Sino Biological Species Human

Human CSF1 ORF clone(NM_172212.2) - CDCL183735 from Creative biogene Species Human

Human CSF1 ORF clone (NM_172210.2) - CDCR051024 from Creative biogene Species Human

Human CSF1 ORF Clone (BC021117) - CDCS405884 from Creative biogene Species Human Accession P09603

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