CSF1

Gene Symbol	CSF1
Entrez Gene	1435
Alt Symbol	CSF-1, MCSF
Species	Human
Gene Type	protein-coding
Description	colony stimulating factor 1 (macrophage)
Other Description	lanimostim|macrophage colony-stimulating factor 1
Swissprots	Q9UQR8 Q5VVF3 Q14806 Q14086 A8K6J5 Q13130 Q5VVF4 P09603
Accessions	AAB59527 CAA29479 CAJ32234 CAJ32235 CAJ32236 CBX54357 CBX55878 CBX55879 CBX55880 CCA65433 CCA65434 CCA65435 EAW56416 EAW56417 EAW56418 EAW56419 EAW56420 EAW56421 P09603 AB208952 BAD92189 AI758702 AK291660 BAF84349 AK300401 BAG62132 AK311440 BC021117 AAH21117 DA414355 DB287787 JF803735 AEF12310 M27087 AAA59573 M37435 AAA52117 M64592 AAA59572 M76453 AAA52120 U22386 AAA64849 X05825 CAA29265 NM_000757 NP_000748 NM_172210 NP_757349 NM_172211 NP_757350 NM_172212 NP_757351
Function	Cytokine that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. Required for normal male and female fertility. Promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. Plays a role in lipoprotein clearance. {ECO:0000269|PubMed:16337366, ECO:0000269|PubMed:19934330, ECO:0000269|PubMed:20504948, ECO:0000269|PubMed:20829061}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:1531650, ECO:0000269|PubMed:3264877}; Single-pass type I membrane protein {ECO:0000269|PubMed:1531650, ECO:0000269|PubMed:3264877}.
Top Pathways	Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, Osteoclast differentiation, Rheumatoid arthritis, PI3K-Akt signaling pathway

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CSF1-Over-expression-Lysate - LY10062a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

CSF1 293T Cell Transient Overexpression Lysate(Denatured) - H00001435-T01 from Acris Antibodies Category Cell Lysate Prices $320.00 Sizes 100 µl

CSF1 overexpression lysate - LY403534 from Acris Antibodies Category Cell Lysate Prices $480.00 Sizes 100 µg

CSF1 overexpression lysate - LY406741 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

CSF1 293 Cell Lysate - 410143 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

CSF1 293 Cell Lysate - 404018 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

M-CSF Overexpression Lysate (Denatured) - H00001435-T01 from Novus Biologicals Category Cell Lysate Prices $279.00 Sizes 100 µl

M-CSF Overexpression Lysate (Native) - NBL1-09513 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

CSF1 Over-expression Lysate Product - GWB-858D30 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

CSF1 Over-expression Lysate Product - GWB-1C7658 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Human M-CSF / CSF-1 HEK293 Cell Lysate (WB positive control) - 11792-HNAHL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human M-CSF / CSF-1 HEK293 Cell Lysate (WB positive control) - 11792-H08H1L-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human M-CSF / CSF-1 HEK293 Cell Lysate (WB positive control) - 11792-H02HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

Human / Cynomolgus M-CSF / CSF-1 HEK293 Cell Lysate (WB positive control) - 11792-H08HL-300 from Sino Biological Category Cell Lysate Prices $195.00 Sizes 300 µg Species Human

M-CSF Overexpression Lysate (Native) - NBP2-05169 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

M-CSF Overexpression Lysate (Native) - NBP2-05168 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

Panoply™ Human CSF1 Knockdown Stable Cell Line - CSC-DC003699 from Creative biogene Category Cell Line Species Human

CSF1 Knockout Cell Line-HeLa - CSC-RT1988 from Creative biogene Category Cell Line Species Human

CSF1 KO Cell Lysate-HeLa - CLKO-1848 from Creative biogene Category Cell Lysate

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