RNLS

Gene Symbol	RNLS
Entrez Gene	55328
Alt Symbol	C10orf59, RENALASE
Species	Human
Gene Type	protein-coding
Description	renalase, FAD-dependent amine oxidase
Other Description	MAO-C|alpha-NAD(P)H oxidase/anomerase|monoamine oxidase-C|renalase
Swissprots	Q5VYX0 Q9NUP8 Q9BS33
Accessions	AEW43431 AEW43432 EAW50167 EAW50168 EAW50169 EAW50170 EAW50171 Q5VYX0 AA854849 AK002080 BAA92073 AK296262 BAG58975 BC005364 AAH05364 BM978857 BP332262 BX648154 HQ448189 ADQ32670 XM_005269946 XP_005270003 XM_005269947 XP_005270004 XM_005269948 XP_005270005 XM_005269949 XP_005270006 XM_005269950 XP_005270007 XM_011539924 XP_011538226 XM_011539925 XP_011538227 XM_011539926 XP_011538228 XM_011539927 XP_011538229 NM_001031709 NP_001026879 NM_018363 NP_060833
Function	Catalyzes the oxidation of the less abundant alpha- NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. {ECO:0000269|PubMed:15841207, ECO:0000269|PubMed:17385068}.
Subcellular Location	Secreted {ECO:0000269|PubMed:15841207}.
Tissue Specificity	Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects. {ECO:0000269|PubMed:15841207}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RNLS / Renalase ELISA Kit (Sandwich ELISA) - LS-F6759 from LifeSpan Bioscience Category ELISA Kit Prices $720.00 Sizes 1 plate Sensitivity 1.38 ng/ml Range 3.13-200 ng/ml

Rat RNLS / Renalase ELISA Kit (Sandwich ELISA) - LS-F8901 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 0.62 ng/ml Range 3.13-200 ng/ml

Mouse RNLS / Renalase ELISA Kit (Sandwich ELISA) - LS-F12510 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 1.56 Range 3.13-200 ng/ml

Rat RNLS / Renalase ELISA Kit (Sandwich ELISA) - LS-F12509 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 3.12 Range 3.13-200 ng/ml

Human RNLS / Renalase ELISA Kit (Sandwich ELISA) - LS-F12508 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 Range 3.13-200 ng/ml

Renalase (RNLS), Human, ELISA Kit - SEC845Hu from ARP American Research Products Category ELISA Kit Prices $720.00 Sizes 96 t Sensitivity 3.6ng/mL Range 7.8-500ng/mL

Renalase, RNLS, Human, ELISA Kit - E1103h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Renalase/ Monoamine Oxidase-C (RNLS/ MAO-C), Human, ELISA Kit - CSB-E13945h from ARP American Research Products Category ELISA Kit Prices $550.00, $790.00, $791.00, $794.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

chromosome 10 open reading frame 59, ELISA Kit - MBS707117 from MyBioSource Category ELISA Kit Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity The minimum detectable dose of rat RNLS is typically less than 15.6 ng/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations. Range 62.5 ng/ml -4000 ng/ml.

chromosome 10 open reading frame 59, ELISA Kit - MBS703138 from MyBioSource Category ELISA Kit Prices $250.00, $550.00, $795.00, $2,890.00, $5,465.00 Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.156 ug/ml Range 0.625 ug/ml-40 ug/ml

Renalase, ELISA Kit - MBS086540 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS079378 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells Sensitivity 0.1 ug/ml. Range 0.625 ug/ml - 20 ug/ml.

Renalase, ELISA Kit - MBS107028 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS060186 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS097059 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS054056 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS066347 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS064302 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS082241 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS087617 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS066132 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS070000 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS048773 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS061345 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Renalase, ELISA Kit - MBS082355 from MyBioSource Category ELISA Kit Prices $435.00, $600.00, $2,650.00, $5,205.00 Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

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