RNLS

Gene Symbol	RNLS
Entrez Gene	55328
Alt Symbol	C10orf59, RENALASE
Species	Human
Gene Type	protein-coding
Description	renalase, FAD-dependent amine oxidase
Other Description	MAO-C|alpha-NAD(P)H oxidase/anomerase|monoamine oxidase-C|renalase
Swissprots	Q5VYX0 Q9NUP8 Q9BS33
Accessions	AEW43431 AEW43432 EAW50167 EAW50168 EAW50169 EAW50170 EAW50171 Q5VYX0 AA854849 AK002080 BAA92073 AK296262 BAG58975 BC005364 AAH05364 BM978857 BP332262 BX648154 HQ448189 ADQ32670 XM_005269946 XP_005270003 XM_005269947 XP_005270004 XM_005269948 XP_005270005 XM_005269949 XP_005270006 XM_005269950 XP_005270007 XM_011539924 XP_011538226 XM_011539925 XP_011538227 XM_011539926 XP_011538228 XM_011539927 XP_011538229 NM_001031709 NP_001026879 NM_018363 NP_060833
Function	Catalyzes the oxidation of the less abundant alpha- NAD(P)H isoform to form beta-NAD(P)(+). The enzyme hormone is secreted by the kidney, and circulates in blood and modulates cardiac function and systemic blood pressure. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis. {ECO:0000269|PubMed:15841207, ECO:0000269|PubMed:17385068}.
Subcellular Location	Secreted {ECO:0000269|PubMed:15841207}.
Tissue Specificity	Secreted into the blood by the kidney. Highly expressed in the kidney, expressed at lower level in heart, skeletal muscle and small intestine. Its plasma concentration is markedly reduced in patients with end-stage renal disease, as compared with healthy subjects. {ECO:0000269|PubMed:15841207}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Renalase (V-20) - sc-79593 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Renalase (H-241) - sc-366165 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

Renalase (N-15) - sc-79590 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-Renalase antibody - ab31291 from Abcam Prices $385.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-Renalase antibody - ab168408 from Abcam Prices $376.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-Renalase antibody - ab91465 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-Renalase antibody - ab128261 from Abcam Prices $376.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-Renalase antibody [EPR4212(2)] - ab178700 from Abcam Prices $385.00 Sizes 100 µl Host Rabbit Clonality Monoclonal Clone EPR4212(2)

Anti-RNLS / Renalase Antibody (aa18-150) - LS-C314936 from LifeSpan Bioscience Prices $425.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa134-147) - LS-C55378 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa18-150, Biotin) - LS-C299747 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa160-319, FITC) - LS-C303308 from LifeSpan Bioscience Prices $455.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa160-319, Biotin) - LS-C300426 from LifeSpan Bioscience Prices $435.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody - LS-C309649 from LifeSpan Bioscience Prices $475.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa18-150, FITC) - LS-C303951 from LifeSpan Bioscience Prices $465.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa224-233) - LS-C55379 from LifeSpan Bioscience Prices $395.00 Sizes 100 µg Host Goat Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa161-210) - LS-C146530 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa160-319) - LS-C296217 from LifeSpan Bioscience Prices $405.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RNLS / Renalase Antibody (aa18-150) - LS-C296218 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Renalase Antibody - AF5350 from Novus Biologicals Prices $329.00 Sizes 100 µg Host Goat Clonality Polyclonal

Renalase Antibody - NB100-1493 from Novus Biologicals Prices $299.00 Sizes 100 µg Host Goat Clonality Polyclonal

Renalase Antibody - NB100-93435 from Novus Biologicals Prices $299.00 Sizes 100 µg Host Goat Clonality Polyclonal

Renalase Antibody - H00055328-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

Anti-RNLS antibody produced in rabbit - SAB4300863 from Sigma-Aldrich Prices $230.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RNLS (136-150) antibody produced in rabbit - SAB1102225 from Sigma-Aldrich Prices $298.50 Sizes 200 µl Host Rabbit Clonality Polyclonal

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