TMEFF2

Gene Symbol TMEFF2
Entrez Gene 23671
Alt Symbol CT120.2, HPP1, TENB2, TPEF, TR, TR-2
Species Human
Gene Type protein-coding
Description transmembrane protein with EGF-like and two follistatin-like domains 2
Other Description cancer/testis antigen family 120, member 2|hyperplastic polyposis protein 1|tomoregulin|tomoregulin-2|transmembrane protein TENB2
Swissprots Q9UK65 Q53H90 Q9P2Y9 Q2FA44 Q9UIK5 Q8N2R5 Q9NSS5 Q4ZFW4 Q53RE1 Q9NR15
Accessions AAF91397 AAG49451 AAX88893 AAY14874 CAH05705 CAR82354 CCQ43534 EAX10831 EAX10832 Q9UIK5 AB004064 BAA90820 AB017269 BAA87897 AF179274 AAD55776 AF242222 AAG49452 AK054646 AK074507 BAC11030 AK074632 BAG51979 AK222691 BAD96411 AK315376 BAG37769 AL157430 CAB75654 AY358907 AAQ89266 BC008973 AAH08973 CR457390 CAG33671 DQ133599 AAZ43216 DQ668381 XM_005246437 XP_005246494 XM_011510890 XP_011509192 NM_001305134 NP_001292063 NM_001305145 NP_001292074 NM_016192 NP_057276
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:17942404}.
Subcellular Location Isoform 3: Secreted.
Tissue Specificity Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:10987305, ECO:0000269|PubMed:11120884, ECO:0000269|PubMed:11668495, ECO:0000269|PubMed:16439095, ECO:0000269|PubMed:16805794}.

TMEFF2 (E-12) - sc-376175 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
TMEFF2 (E-12): sc-376175. Western blot analysis of TMEFF2 expression in LNCaP whole cell lysate.

TMEFF2 (C-19) - sc-47502 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TMEFF2 (H-63) - sc-135250 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
TMEFF2 (H-63): sc-135250. Western blot analysis of TMEFF2 expression in mouse brain tissue extract.

TMEFF2 (N-15) - sc-47504 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

TMEFF2 (J4B6) - sc-135812 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Mouse
Clonality Monoclonal
TMEFF2 (J4B6): sc-135812. Western blot analysis of TMEFF2 expression in mouse brain tissue extract (A) and HeLa whole cell lysate (B).

Anti-TMEFF2 antibody [EPR6385] - ab124775 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6385
All lanes : Anti-TMEFF2 antibody [EPR6385] (ab124775) at 1/1000 dilutionLane 1 : HeLa lysateLane 2 : SW480 lysateLane 3 : Human prostate lysateLysates/proteins at 10 µg per lane.SecondaryHRP labelled Goat anti Rabbit at 1/2000 dilution

Anti-TMEFF2 antibody [EPR6386] - ab133562 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6386
Immunohistochemical analysis of formailin-fixed, paraffin-embedded Human prostatic hyperplasia tissue staining TMEFF2 using ab133562 at a 1/50 dilution.

Anti-TMEFF2 Antibody (Extracellular Domain, clone EPR6385) - LS-C138961 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6385
Western blot analysis on (A) HeLa, (B) SW480, and (C) human prostate lysates using anti-TMEFF2 antibody.

Anti-TMEFF2 Antibody (aa52-290) - LS-C315033 from LifeSpan Bioscience

Prices $425.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of recombinant TMEFF2.

Anti-TMEFF2 Antibody (aa204-253) - LS-C201525 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human Colorectal Tumor. TMEFF2 antibody dilution 1.0 ug/ml.

Anti-TMEFF2 Antibody (aa41-150, clone J4B6) - LS-C93807 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone J4B6
Cell lysates of Mouse brain and HeLa (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human TMEFF2 (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-TMEFF2 Antibody (clone 3H8) - LS-C337673 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3H8
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TMEFF2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TMEFF2.

Anti-TMEFF2 Antibody (clone 1A9) - LS-C337662 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1A9
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TMEFF2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TMEFF2.

Anti-TMEFF2 Antibody (Intracellular Domain, clone EPR6386) IHC-plus™ - LS-B7762 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Monoclonal
Clone EPR6386
Anti-TMEFF2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B7762 dilution 1:25.

Anti-TMEFF2 Antibody (clone 4G2) - LS-C173625 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 4G2
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TMEFF2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TMEFF2.

Anti-TMEFF2 Antibody (clone 3D1) - LS-C173624 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 3D1
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TMEFF2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TMEFF2.

Anti-TMEFF2 Antibody (clone 1E4) - LS-C173849 from LifeSpan Bioscience

Prices $350.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E4
Anti-TMEFF2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TMEFF2.

Anti-TMEFF2 Antibody (clone 1E1) - LS-C173848 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1E1
Anti-TMEFF2 mouse monoclonal antibody immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY TMEFF2.

Anti-TMEFF2 Antibody (clone 1B4) - LS-C173807 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1B4
IHC of paraffin-embedded Human tonsil using anti-TMEFF2 mouse monoclonal antibody.

Anti-TMEFF2 Antibody (clone 1F9) - LS-C337664 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F9
IHC of paraffin-embedded Human tonsil using anti-TMEFF2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).

Anti-TMEFF2 Antibody (aa41-150) - LS-C124697 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

TMEFF2/Tomoregulin-2 Antibody (1F9) - NBP2-01863 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1F9
Western Blot: TMEFF2 Antibody (1F9) [NBP2-01863] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TMEFF2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TMEFF2.

TMEFF2/Tomoregulin-2 Antibody (J4B6) - NBP1-07100 from Novus Biologicals

Prices $279.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone J4B6
Western Blot: TMEFF2/Tomoregulin-2 Antibody (J4B6) [NBP1-07100] - The Cell lysate (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human TMEFF2 antibody (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Lane 1.: SW480 cell lysate

DISC1 Antibody (685920) - MAB6699 from Novus Biologicals

Prices $99.00, $249.00
Sizes 25 µg, 100 µg
Host Mouse
Clonality Monoclonal
Clone 685920
Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, Raji human Burkitt's lymphoma cell line, Daudi human Burkitt's lymphoma cell line, and Ramos human Burkitt's lymphoma cell line. PVDF membrane was probed with 2 µg/mL of Mouse Anti-Human DISC1 Monoclonal Antibody (Catalog # MAB6699) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF007). A specific band was detected for DISC1 at approximately 100 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

TMEFF2/Tomoregulin-2 Antibody - AF1867 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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