TMEFF2

Gene Symbol TMEFF2
Entrez Gene 23671
Alt Symbol CT120.2, HPP1, TENB2, TPEF, TR, TR-2
Species Human
Gene Type protein-coding
Description transmembrane protein with EGF-like and two follistatin-like domains 2
Other Description cancer/testis antigen family 120, member 2|hyperplastic polyposis protein 1|tomoregulin|tomoregulin-2|transmembrane protein TENB2
Swissprots Q9UK65 Q53H90 Q9P2Y9 Q2FA44 Q9UIK5 Q8N2R5 Q9NSS5 Q4ZFW4 Q53RE1 Q9NR15
Accessions AAF91397 AAG49451 AAX88893 AAY14874 CAH05705 CAR82354 CCQ43534 EAX10831 EAX10832 Q9UIK5 AB004064 BAA90820 AB017269 BAA87897 AF179274 AAD55776 AF242222 AAG49452 AK054646 AK074507 BAC11030 AK074632 BAG51979 AK222691 BAD96411 AK315376 BAG37769 AL157430 CAB75654 AY358907 AAQ89266 BC008973 AAH08973 CR457390 CAG33671 DQ133599 AAZ43216 DQ668381 XM_005246437 XP_005246494 XM_011510890 XP_011509192 NM_001305134 NP_001292063 NM_001305145 NP_001292074 NM_016192 NP_057276
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:17942404}.
Subcellular Location Isoform 3: Secreted.
Tissue Specificity Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:10987305, ECO:0000269|PubMed:11120884, ECO:0000269|PubMed:11668495, ECO:0000269|PubMed:16439095, ECO:0000269|PubMed:16805794}.

transmembrane protein with EGF-like and two follistatin-like domains 2, ELISA Kit - MBS928793 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity The minimum detectable dose of human TMEFF2 is typically less than 7 pg/ml. The sensitivity of this assay, or Lower Limit of Detection (LLD) was defined as the lowest protein concentration that could be differentiated from zero. It was determined the mean O.D value of 20 replicates of the zero standard added by their three standard deviations.
Range 28 pg/ml -1800 pg/ml.

Tomoregulin-2 (TMEFF2), ELISA Kit - MBS9305123 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human Tomoregulin-2(TMEFF2) ELISA kit - CSB-EL023667HU from Cusabio

Category ELISA Kit
Sensitivity 7 pg/ml
Range 28 pg/ml-1800 pg/ml

Human Tomoregulin-2 (TMEFF2) ELISA Kit - EKC35819 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 7 pg/ml
Range 28 pg/ml-1800 pg/ml

Human TMEFF2 ELISA Kit - E038591 from Biobool

Category ELISA Kit

TMEFF2 ELISA Kit (Human) (OKCA00841) - OKCA00841 from Aviva Systems Biology

Category ELISA Kit
Prices $590.00
Sizes 96 wells
Sensitivity 7 pg/mL
Range 28 pg/mL-1,800 pg/mL

Human TMEFF2 ELISA Kit - orb405425 from Biorbyt

Category ELISA Kit
Sensitivity 7 pg/ml
Range 28 pg/ml-1800 pg/ml
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