TMEFF2

Gene Symbol	TMEFF2
Entrez Gene	23671
Alt Symbol	CT120.2, HPP1, TENB2, TPEF, TR, TR-2
Species	Human
Gene Type	protein-coding
Description	transmembrane protein with EGF-like and two follistatin-like domains 2
Other Description	cancer/testis antigen family 120, member 2|hyperplastic polyposis protein 1|tomoregulin|tomoregulin-2|transmembrane protein TENB2
Swissprots	Q9UK65 Q53H90 Q9P2Y9 Q2FA44 Q9UIK5 Q8N2R5 Q9NSS5 Q4ZFW4 Q53RE1 Q9NR15
Accessions	AAF91397 AAG49451 AAX88893 AAY14874 CAH05705 CAR82354 CCQ43534 EAX10831 EAX10832 Q9UIK5 AB004064 BAA90820 AB017269 BAA87897 AF179274 AAD55776 AF242222 AAG49452 AK054646 AK074507 BAC11030 AK074632 BAG51979 AK222691 BAD96411 AK315376 BAG37769 AL157430 CAB75654 AY358907 AAQ89266 BC008973 AAH08973 CR457390 CAG33671 DQ133599 AAZ43216 DQ668381 XM_005246437 XP_005246494 XM_011510890 XP_011509192 NM_001305134 NP_001292063 NM_001305145 NP_001292074 NM_016192 NP_057276
Function	May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:17942404}.
Subcellular Location	Isoform 3: Secreted.
Tissue Specificity	Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:10987305, ECO:0000269|PubMed:11120884, ECO:0000269|PubMed:11668495, ECO:0000269|PubMed:16439095, ECO:0000269|PubMed:16805794}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TMEFF2 Gene ORF cDNA clone in cloning vector - HG11006-M from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG11006-CM from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG11006-CY from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG11006-NY from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, N-His tag - HG11006-NH from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid - HG11006-UT from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, C-His tag - HG11006-CH from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG11006-ACG from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11006-M-F from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG11006-NF from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG11006-NM from Sino Biological Species Human

Human TMEFF2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG11006-CF from Sino Biological Species Human

Human TMEFF2 ORF clone(NM_016192.2) - CDCL186495 from Creative biogene Species Human

Human Tomoregulin-2 Gene - orb91548 from Biorbyt Prices $264.00 Sizes 10 μg Species Human

Human TMEFF2 cDNA Clone(NM_016192.2) - CDFG000214 from Creative biogene Species Human

Human Tomoregulin-2 Gene - orb145567 from Biorbyt Prices $570.00 Sizes 10 μg Species Human

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