TMEFF2

Gene Symbol	TMEFF2
Entrez Gene	23671
Alt Symbol	CT120.2, HPP1, TENB2, TPEF, TR, TR-2
Species	Human
Gene Type	protein-coding
Description	transmembrane protein with EGF-like and two follistatin-like domains 2
Other Description	cancer/testis antigen family 120, member 2|hyperplastic polyposis protein 1|tomoregulin|tomoregulin-2|transmembrane protein TENB2
Swissprots	Q9UK65 Q53H90 Q9P2Y9 Q2FA44 Q9UIK5 Q8N2R5 Q9NSS5 Q4ZFW4 Q53RE1 Q9NR15
Accessions	AAF91397 AAG49451 AAX88893 AAY14874 CAH05705 CAR82354 CCQ43534 EAX10831 EAX10832 Q9UIK5 AB004064 BAA90820 AB017269 BAA87897 AF179274 AAD55776 AF242222 AAG49452 AK054646 AK074507 BAC11030 AK074632 BAG51979 AK222691 BAD96411 AK315376 BAG37769 AL157430 CAB75654 AY358907 AAQ89266 BC008973 AAH08973 CR457390 CAG33671 DQ133599 AAZ43216 DQ668381 XM_005246437 XP_005246494 XM_011510890 XP_011509192 NM_001305134 NP_001292063 NM_001305145 NP_001292074 NM_016192 NP_057276
Function	May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:17942404}.
Subcellular Location	Isoform 3: Secreted.
Tissue Specificity	Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:10987305, ECO:0000269|PubMed:11120884, ECO:0000269|PubMed:11668495, ECO:0000269|PubMed:16439095, ECO:0000269|PubMed:16805794}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TMEFF2 full length protein - ab161743 from Abcam Category Protein Source Wheat germ Species Human

Human TMEFF2 peptide - ab50025 from Abcam Category Peptide

Human TMEFF2 protein fragment - ab161744 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human TMEFF2/Tomoregulin-2 Protein - H00023671-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human TMEFF2/Tomoregulin-2 Protein - H00023671-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

Tomoregulin-2 / TMEFF2 - H00023671-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

Tomoregulin-2 / TMEFF2 - H00023671-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Tomoregulin-2 / TMEFF2 - H00023671-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Tomoregulin-2 / TMEFF2 - H00023671-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

TMEFF2 fusion protein - ag17427 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

TMEFF2 fusion protein - ag2609 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Tomoregulin (TR) - RPM378Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Tomoregulin (TR) - RPM378Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Human Tomoregulin-2(TMEFF2) - CSB-YP883439HU CSB-EP883439HU CSB-BP883439HU CSB-MP883439HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Tomoregulin Protein (Recombinant) - abx166494 from Abbexa Category Protein Source Human Species Human

TMEFF2/Tomoregulin-2 Recombinant Protein Antigen - NBP1-84362PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

TMEFF2 Peptide, Human - M34GP16065H from Creative Peptides Category Peptide Source Synthetic. Species Human

Recombinant Tomoregulin (TR) - RPU51642 from Biomatik Category Protein Prices $176.00, $360.00, $550.00, $656.00 Sizes 10 µg, 50 µg, 100 µg, 200 µg Source E.coli Species Human

TMEFF2 Recombinant Protein (OPCD07630) - OPCD07630 from Aviva Systems Biology Category Protein Source E.coli Species Human

Search more