TMEFF2

Gene Symbol TMEFF2
Entrez Gene 23671
Alt Symbol CT120.2, HPP1, TENB2, TPEF, TR, TR-2
Species Human
Gene Type protein-coding
Description transmembrane protein with EGF-like and two follistatin-like domains 2
Other Description cancer/testis antigen family 120, member 2|hyperplastic polyposis protein 1|tomoregulin|tomoregulin-2|transmembrane protein TENB2
Swissprots Q9UK65 Q53H90 Q9P2Y9 Q2FA44 Q9UIK5 Q8N2R5 Q9NSS5 Q4ZFW4 Q53RE1 Q9NR15
Accessions AAF91397 AAG49451 AAX88893 AAY14874 CAH05705 CAR82354 CCQ43534 EAX10831 EAX10832 Q9UIK5 AB004064 BAA90820 AB017269 BAA87897 AF179274 AAD55776 AF242222 AAG49452 AK054646 AK074507 BAC11030 AK074632 BAG51979 AK222691 BAD96411 AK315376 BAG37769 AL157430 CAB75654 AY358907 AAQ89266 BC008973 AAH08973 CR457390 CAG33671 DQ133599 AAZ43216 DQ668381 XM_005246437 XP_005246494 XM_011510890 XP_011509192 NM_001305134 NP_001292063 NM_001305145 NP_001292074 NM_016192 NP_057276
Function May be a survival factor for hippocampal and mesencephalic neurons. The shedded form up-regulates cancer cell proliferation, probably by promoting ERK1/2 phosphorylation. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:17942404}.
Subcellular Location Isoform 3: Secreted.
Tissue Specificity Highly expressed in adult and fetal brain, spinal cord and prostate. Expressed in all brain regions except the pituitary gland, with highest levels in amygdala and corpus callosum. Expressed in the pericryptal myofibroblasts and other stromal cells of normal colonic mucosa. Expressed in prostate carcinoma. Down-regulated in colorectal cancer. Present in Alzheimer disease plaques (at protein level). Isoform 3 is expressed weakly in testis and at high levels in normal and cancerous prostate. {ECO:0000269|PubMed:10903839, ECO:0000269|PubMed:10987305, ECO:0000269|PubMed:11120884, ECO:0000269|PubMed:11668495, ECO:0000269|PubMed:16439095, ECO:0000269|PubMed:16805794}.

TMEFF2 CRISPR/Cas9 KO Plasmid (h) - sc-404536 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 HDR Plasmid (h) - sc-404536-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 Double Nickase Plasmid (h) - sc-404536-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 Double Nickase Plasmid (h2) - sc-404536-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 CRISPR Activation Plasmid (h) - sc-404536-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 CRISPR Activation Plasmid (h2) - sc-404536-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 Lentiviral Activation Particles (h) - sc-404536-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 Lentiviral Activation Particles (h2) - sc-404536-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TMEFF2 siRNA (h) - sc-61695 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TMEFF2 shRNA Plasmid (h) - sc-61695-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TMEFF2 shRNA (h) Lentiviral Particles - sc-61695-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU119081 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21463 from Sigma-Aldrich

Category ZFN Kit

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21463 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

TMEFF2 siRNA (Human) - CRH8431 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMEFF2 - MBS8237441 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TMEFF2 (NM_016192.2) - SHH428688 from Creative biogene

Category siRNA
Species Reactivities Human

Human TMEFF2 siRNA - orb268933 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TMEFF2 shRNA Plasmid (Human) - CHH8431 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TMEFF2 miRNA 3'UTR clone - MiUTR1H-10468 from Creative biogene

Species Reactivities Human
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